Balafrej M, Kahn M F, Vigneron A M, Bourgeois P
Ann Med Interne (Paris). 1987;138(3):185-8.
The authors report three identical cases of the association of acrosclerosis with telangiectasis without calcinosis, Sjögren-Gougerot syndrome, myxoedema with antithyroid antibodies and anti-centromere antibodies. The association of these conditions one with another has already been published, but, to the authors' best knowledge, this is the first report of all of them grouped together in the same patients. With reference to the literature, the authors discuss the problems of individualization of the CRST syndrome and its varieties and the clinical significance of the presence of anti-centromere antibodies.
作者报告了3例相同病例，这些病例均表现为无钙质沉着的肢端硬化与毛细血管扩张、干燥综合征、伴有抗甲状腺抗体和抗着丝点抗体的黏液性水肿并存。这些病症相互之间的关联此前已有报道，但据作者所知，这是首次在同一患者中发现所有这些病症同时出现的报告。作者参考相关文献，讨论了CRST综合征及其亚型的个体化问题以及抗着丝点抗体存在的临床意义。
