镰状细胞性肝病患者对羟基脲的反应：一例报告
Response to Hydroxyurea in a Patient With Sickle Cell Hepatopathy: A Case Report.
作者信息
Safhi Maha A, Baghdadi Rana M, Al-Marzouki Adel F, Al-Sayes Fatin
机构信息
Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
Internal Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
出版信息
Cureus. 2021 Dec 23;13(12):e20649. doi: 10.7759/cureus.20649. eCollection 2021 Dec.
Abstract
Sickle cell hepatopathy is an underreported entity lacking clear management guidelines. This case highlights the potential role of hydroxyurea (HU) in improving the hepatic dysfunction seen among patients with sickle cell disease (SCD). We herein present the clinical course of a patient prior to and after the initiation of hydroxyurea with an emphasis on long-term outcomes and the patterns of liver injury over a 15-year time course.
摘要
镰状细胞性肝病是一种报告不足且缺乏明确管理指南的疾病。本病例突出了羟基脲（HU）在改善镰状细胞病（SCD）患者肝功能障碍方面的潜在作用。我们在此介绍一名患者在开始使用羟基脲之前和之后的临床病程，重点关注15年时间跨度内的长期结局和肝损伤模式。
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