Huskisson E C
Eur J Rheumatol Inflamm. 1987;8(1):3-5.
The anti-inflammatory era opened with aspirin, which for decades was the first-line treatment for rheumatoid arthritis. Striking advances have occurred in recent years with the introduction of propionic acid derivatives like ibuprofen and once-a-day drugs like piroxicam. The class now includes a range of drugs with properties suited to the range of clinical indications presented by rheumatic disorders. Anti-inflammatory drugs are now and will continue to be the mainstay of symptomatic therapy for arthritis.
抗炎时代始于阿司匹林,几十年来它一直是类风湿关节炎的一线治疗药物。近年来,随着布洛芬等丙酸衍生物以及吡罗昔康等每日一次用药的引入,取得了显著进展。现在这一类药物包括一系列具有适合风湿性疾病临床指征特性的药物。抗炎药物现在是且将继续是关节炎症状性治疗的主要手段。