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进行性核上性麻痹的不寻常表现。

An Unusual Presentation of Progressive Supranuclear Palsy.

机构信息

Department of Neurology, Jagiellonian University, Medical College, Kraków, Poland.

Health Institute Dr Boczarska-Jedynak, Oswiecim, Poland.

出版信息

Neurol India. 2021 Nov-Dec;69(6):1789-1793. doi: 10.4103/0028-3886.333499.

Abstract

Progressive supranuclear palsy (PSP) is a neurodegenerative disorder with varied manifestations. Progressive gait freezing (PGF) is considered to be a rare and uncommon presentation of PSP. Here we present 2 patients with freezing of gait as the initial manifestation of PSP-PGF. One patient fulfilled the criteria of PSP-PGF, while the second did not. Nevertheless, according to the movement disorders society-PSP criteria, he met the threshold for possible PSP with progressive gait freezing. We emphasize a broad PSP-PGF spectrum of symptoms and sensitize to the fact that freezing of backward gait could indeed represent an unusual manifestation of atypical parkinsonism.

摘要

进行性核上性麻痹(PSP)是一种表现多样的神经退行性疾病。进行性步态冻结(PGF)被认为是 PSP 的一种罕见和不常见的表现。在这里,我们介绍了 2 例以步态冻结为首发表现的 PSP-PGF 患者。1 例患者符合 PSP-PGF 的标准,而另 1 例则不符合。然而,根据运动障碍协会 PSP 标准,他符合可能的 PSP 伴有进行性步态冻结的阈值。我们强调了 PSP-PGF 症状的广泛谱,并提醒人们后退性步态冻结实际上可能代表非典型帕金森病的一种不寻常表现。

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