Management Department of Biosafety, Laboratory Animal, and Pathogen Bank, National Institute of Infectious Diseases, Japan.
ALBAR NET Co. Ltd, Japan.
Jpn J Infect Dis. 2022 Jul 22;75(4):341-346. doi: 10.7883/yoken.JJID.2021.663. Epub 2021 Dec 28.
Several studies have reported on the effectiveness of various disinfection methods for severe acute respiratory syndrome coronavirus 2 and their applicability to the disinfection of N95 respirators and surgical masks. To date, there have been no reports on the decontamination of deep in the intermediate layers of the multilayered structure. In this study, the conditions required for decontamination of such layers were simulated by considering the thickness and shape of N95 respirators or surgical masks (samples). After applying heat (steam, dry heat, or hot water) at 75°C for 60 min or chemical (benzalkonium chloride or laundry detergent) treatment, the collection efficiency of the samples was evaluated. Following the dry heat treatment, the time between the treatment and heat reaching the intermediate layer of the filter fiber was extended by 10 min. A dry heat disinfection method that combines hot water and a closed container was also evaluated, and satisfactory conditions were extended by 60 min. For each heat treatment, there was almost no effect on the collection efficiency, although there were cases where deformation was caused by mechanical stress. In contrast, chemical treatment resulted in a reduction in the collection efficiency of smaller particles.
已有多项研究报告了针对严重急性呼吸综合征冠状病毒 2 的各种消毒方法的有效性及其在 N95 口罩和外科口罩消毒方面的适用性。迄今为止，尚未有关于多层结构深层中间层消毒的报道。在这项研究中，通过考虑 N95 口罩或外科口罩（样品）的厚度和形状，模拟了对这些层进行消毒所需的条件。在 75°C 下加热（蒸汽、干热或热水）60 分钟或化学（苯扎氯铵或洗衣液）处理后，评估了样品的收集效率。在干热处理之后，将处理与热量到达过滤纤维中间层之间的时间延长了 10 分钟。还评估了一种结合热水和封闭容器的干热消毒方法，将时间延长至 60 分钟，结果令人满意。对于每种热处理，对收集效率几乎没有影响，尽管在某些情况下会因机械应力而导致变形。相比之下，化学处理会导致较小颗粒的收集效率降低。
