Department of Gastroenterology, Dokkyo Medical University, Japan.
Institutional Research Center, Dokkyo Medical University, Japan.
Intern Med. 2022 Jul 15;61(14):2149-2153. doi: 10.2169/internalmedicine.8573-21. Epub 2021 Dec 28.
Photodynamic therapy is useful as organ-preservation salvage therapy for residual recurrence of esophageal squamous cell carcinoma after chemoradiation therapy. However, the high residual recurrence rate of photodynamic therapy poses a problem. We herein report a patient who underwent photodynamic therapy for recurrence of superficial esophageal squamous cell carcinoma after chemoradiation therapy. The patient later exhibited another episode of recurrence of superficial esophageal squamous cell carcinoma, and R0 curative resection was obtained with endoscopic submucosal dissection. This suggests that endoscopic submucosal dissection may be an effective treatment option that can achieve R0 resection even for residual superficial cancer after salvage photodynamic therapy.
光动力疗法对于放化疗后食管鳞癌残留复发是一种有用的器官保存挽救治疗方法。然而，光动力疗法的高残留复发率是一个问题。我们在此报告一例患者，该患者在放化疗后复发浅表性食管鳞癌，行光动力疗法治疗。患者后来又出现一次浅表性食管鳞癌复发，行内镜黏膜下剥离术获得了 R0 治愈性切除。这表明内镜黏膜下剥离术可能是一种有效的治疗选择，即使对于挽救性光动力治疗后的残留浅表性癌，也可以实现 R0 切除。
