Rossi Alfredo, Tadiotto Cicogna Giulia, Caro Gemma, Fortuna Maria Caterina, Magri Francesca, Grassi Sara
Drs. Rossi, Fortuna, Caro, Magri, and Grassi are with the Department of Internal Medicine and Medical Specialties, Dermatology at the Sapienza University of Rome in Rome, Italy.
Dr. Tadiotto Cicogna is with the Unit of Dermatology at the University of Padua in Padua, Italy.
J Clin Aesthet Dermatol. 2021 Sep;14(9):54-58.
Frontal fibrosing alopecia (FFA) is a scarring alopecia that has been reported mostly in postmenopausal women and is characterized by frontotemporal hairline. Currently, there are only a few reports about FFA in male patients.
This study sought to analyze clinical and trichoscopic features of FFA in a case series of men and to describe the main features of FFA in male patients through a review of the literature.
Male patients with clinical and trichoscopical signs of FFA, histologically confirmed, who attended to our clinic from 2014 to 2019 were included in our study. From each patient, clinical and trichoscopic data were collected.
Eight men with an average age of 59 years were recruited. In five patients, serrated hairline recession (i.e., a "zig-zag" pattern) was present, while three presented with linear hairline recession. Also, the eyebrows (n=3 patients), sideburns (n=2 patients), and beard (n=2 patients) were involved. Surprisingly, in two patients, an association with lichen sclerosus (LS) was present.
To the best of our knowledge, this is the first report of a serrated hairline recession pattern in male patients with FFA. A new association between FFA and LS in men was also found. Further studies need to establish the extent of this association and facilitate a better comprehension of the pathophysiologic mechanisms underlying these two diseases.
额部纤维性秃发(FFA)是一种瘢痕性秃发,主要见于绝经后女性,其特征为额颞部发际线。目前,关于男性患者FFA的报道较少。
本研究旨在分析一组男性FFA患者的临床和毛发镜特征,并通过文献回顾描述男性患者FFA的主要特征。
纳入2014年至2019年在我院就诊、临床和毛发镜检查有FFA体征且经组织学证实的男性患者。收集每位患者的临床和毛发镜数据。
招募了8名平均年龄为59岁的男性。5例患者出现锯齿状发际线后移(即“之”字形模式),3例出现直线状发际线后移。此外,眉毛(3例患者)、鬓角(2例患者)和胡须(2例患者)也受累。令人惊讶的是,2例患者合并有硬化性苔藓(LS)。
据我们所知,这是男性FFA患者出现锯齿状发际线后移模式的首例报道。还发现了男性FFA与LS之间的新关联。需要进一步研究以确定这种关联的程度,并有助于更好地理解这两种疾病的病理生理机制。