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[勘误] 活化C激酶1受体(RACK1)通过AKT/mTOR途径促进口腔鳞状细胞癌的进展。

[Corrigendum] Receptor for activated C kinase 1 (RACK1) promotes the progression of OSCC via the AKT/mTOR pathway.

作者信息

Zhang Xuefeng, Liu Na, Ma Danhua, Liu Ling, Jiang Lu, Zhou Yu, Zeng Xin, Li Jing, Chen Qianming

机构信息

State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, P.R. China.

Department of Oral Diseases, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, P.R. China.

出版信息

Int J Oncol. 2022 Feb;60(2). doi: 10.3892/ijo.2022.5301. Epub 2022 Jan 4.

Abstract

Subsequently to the publication of the above article, an interested reader drew to the authors' attention that Fig. 3 (showing how RACK1 silencing alters the protein expression levels of tumor malignant progress markers in OSCC ) contained an overlapping data panel, such that the data were derived from the same original source where they were intending to depict the results from experiments performed under different experimental conditions and Fig. 4 (showing how RACK1 expression is positively correlated with p‑AKT in OSCC tissues and cells) contained a clearly duplicated pair of data panels. The authors were able to re‑examine their original data, and have identified the data that were intended to have been shown for these figure parts. The corrected versions of Figs. 3 and 4 are shown on the next two pages, featuring the correct data for the E‑cadherin experiments in Fig. 3B and the correct enlargement panel for the RACK1 / Moderate dysplasia experiment in Fig. 4A. The authors confirm that these inadvertent errors did not have any major impact on the conclusions reported in their paper, are grateful to the Editor of for allowing them this opportunity to publish a Corrigendum, and apologize to the readership for any inconvenience caused. [the original article was published in 49: 539‑548, 2016; DOI: 10.3892/ijo.2016.3562].

摘要

在上述文章发表之后,一位感兴趣的读者提请作者注意,图3(展示RACK1沉默如何改变口腔鳞状细胞癌中肿瘤恶性进展标志物的蛋白表达水平)包含一个重叠的数据面板,即这些数据源自同一原始来源,而作者本打算用其描绘在不同实验条件下进行的实验结果;图4(展示RACK1表达与口腔鳞状细胞癌组织及细胞中的p-AKT呈正相关)包含一对明显重复的数据面板。作者能够重新检查其原始数据,并已确定了本打算用于这些图部分展示的数据。图3和图4的校正版本见接下来的两页,其中图3B展示了E-钙黏蛋白实验的正确数据,图4A展示了RACK1/中度发育异常实验的正确放大面板。作者确认这些无意的错误对其论文中报道的结论没有任何重大影响,感谢《》杂志编辑给予他们此次发表勘误的机会,并就由此给读者带来的不便表示歉意。[原文发表于《》49: 539 - 548, 2016;DOI: 10.3892/ijo.2016.3562]

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/764c/8759345/603e31b7573e/IJO-60-02-05301-g00.jpg

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