Ann Ital Chir. 2021;92:554-559.
The role of augmented internal anal sphincter (IAS) tone in the genesis of chronic anal fissure (CAF) is still unclear. Lateral internal sphincterotomy (LIS) is the most employed surgical procedure, aiming to reduce the IAS tone leaving a permanent anatomical alteration and it is burdened by high risk post-operative anal incontinence (AI). The aim of this work was to evaluate if the pre-operative manometric alterations of CAFs with hypertonic IAS would normalize after sphincter preserving surgical procedure.
We enrolled 108 consecutive patients affected by idiopathic and non-recurrent CAF undergone fissurectomy and anoplasty with V-Y cutaneous flap advancement and pharmacological sphincterotomy, matched with 54 healthy subject in a 1 to 2 ratio, and followed up for at least for 2 years. The goals were patient's complete healing, the evaluation of AI, recurrence rate and manometry parameters.
All wounds healed within 40 days after surgery. We recorded 7 cases of recurrences healed with medical therapy. We recorded 3 "de novo" post-operative cases of AI all temporary and low grade. Pre-operative values of maximum resting pressure (MRP) and detection of ultraslow wave activity (USWA) were significantly higher than in the healthy control group, but both come back to be similar to those recorded in healthy subject after 24 months from the surgery.
The high healing rate without post-operative "de novo" AI cases with the normalization of manometric parameters suggest that fissurectomy and anoplasty with V-Y cutaneous advancement flap and pharmacological sphincterotomy is an adequate procedure for the treatment of CAF with IAS hypertonia.
Anal fissure, Anoplasty, Fissurectomy, Proctology, Sphincterotomy.
内括约肌张力增高在慢性肛裂(CAF)的发病机制中的作用尚不清楚。外侧内括约肌切开术(LIS)是最常采用的手术方法,旨在降低内括约肌张力,同时留下永久性解剖学改变,并伴有高风险的术后肛门失禁(AI)。本研究旨在评估具有高张力内括约肌的 CAF 患者在接受保留括约肌的手术治疗后,术前的测压改变是否会恢复正常。
我们纳入了 108 例接受肛裂切除术和 V-Y 皮瓣推进肛门成形术及药物性括约肌切开术的特发性和非复发性 CAF 患者,按 1:2 的比例与 54 例健康对照者进行匹配,并随访至少 2 年。目标是患者完全愈合、评估 AI、复发率和测压参数。
所有伤口均在术后 40 天内愈合。我们记录了 7 例复发的病例,均经药物治疗治愈。我们记录了 3 例术后新发的 AI 病例,均为暂时性和低级别。术前最大静息压(MRP)和超慢波活动(USWA)检测值明显高于健康对照组,但在术后 24 个月时均恢复至与健康对照组相似。
高愈合率,无术后新发 AI 病例,测压参数恢复正常,提示肛裂切除术和 V-Y 皮瓣推进肛门成形术及药物性括约肌切开术是治疗伴有内括约肌张力过高的 CAF 的有效方法。
肛裂;肛门成形术;肛裂切除术;直肠肛门病学;括约肌切开术。