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意大利医院和戒毒服务中 HCV 管理的见面-检测-治疗:患者和临床医生的偏好。

Meet-Test-Treat for HCV management: patients' and clinicians' preferences in hospital and drug addiction services in Italy.

机构信息

Infectious Diseases, Polyclinic of Rome Tor Vergata, Rome, Italy.

Infectious Diseases Unit, Department of Mental Health and Public Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.

出版信息

BMC Infect Dis. 2022 Jan 4;22(1):3. doi: 10.1186/s12879-021-06983-y.

Abstract

BACKGROUND

It has been estimated that the incidence of chronic hepatitis C virus (HCV) will not decline over the next 10 years despite the improved efficacy of antiviral therapy because most patients remain undiagnosed and/or untreated. This study aimed to investigate the opinion of relevant target populations on the practicability, effectiveness and best modalities of the test-and-treat approach in the fight against HCV in Italy.

METHODS

A survey was delivered to patients with HCV from the general population, patients from drug addiction services, hospital physicians and healthcare providers for drug addiction services.

RESULTS

For both hospital clinicians and SerD HCPs, tolerability is shown as the most important feature of a suitable treatment. Time to treatment (the time from first contact to initiation of treatment) is deemed important to the success of the strategy by all actors. While a tolerable treatment was the main characteristic in a preferred care pathway for general patients, subjects from drug addiction services indicated that a complete Meet-Test-Treat pathway is delivered within the habitual care center as a main preference. This is also important for SerD HCPs who are a strong reference for their patients; hospital clinicians were less aware of the importance of the patient-HCP relationship in this process.

CONCLUSION

The health system is bound to implement suitable pathways to facilitate HCV eradication. A Meet-Test-Treat program within the drug addiction services may provide good compliance from subjects mainly concerned with virus transmission.

摘要

背景

尽管抗病毒治疗的疗效有所提高,但预计在未来 10 年内,慢性丙型肝炎病毒 (HCV) 的发病率不会下降,因为大多数患者仍未被诊断和/或未得到治疗。本研究旨在调查意大利相关目标人群对 HCV 检测和治疗方法的实用性、有效性和最佳模式的看法。

方法

向普通人群中的 HCV 患者、戒毒服务患者、医院医生和戒毒服务医疗保健提供者发送了一项调查。

结果

对于医院临床医生和 SerD HCP 来说,耐受性被视为合适治疗的最重要特征。所有参与者都认为,从首次接触到开始治疗的治疗时间(从首次接触到开始治疗的时间)对该策略的成功很重要。虽然可耐受的治疗是普通患者首选护理途径的主要特征,但来自戒毒服务的患者表示,在习惯护理中心内提供完整的“检测-治疗”途径是他们的主要偏好。对于 SerD HCP 来说,这也很重要,因为他们是患者的重要参考;而医院临床医生则较少意识到在这个过程中患者与医疗保健提供者关系的重要性。

结论

卫生系统必须实施合适的途径,以促进 HCV 的消除。在戒毒服务中实施“检测-治疗”方案可能会使主要关注病毒传播的患者具有良好的依从性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062b/8725306/87ad06afaf14/12879_2021_6983_Fig1_HTML.jpg

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