Babu Ps Shafin, Marwah Vikas, Katoch Cds, Garg Yadvir, Kumar T Ajai, Sharma Manish, Choudhary Robin, Peter Deepu K, Chopra Manu, Bhati Gaurav
Respiratory Medicine, Army Institute Of Cardio Thoracic Sciences, Pune, IND.
Respiratory Medicine, Army Institute of Cardio Thoracic Sciences, Pune, IND.
Cureus. 2021 Nov 27;13(11):e19940. doi: 10.7759/cureus.19940. eCollection 2021 Nov.
Background A mass lesion in the lung is a common finding seen on chest radiology. The prognosis of patients with mass lesions in the lung is capricious as malignancy is a consideration. It is essential to diagnose the underlying aetiology at the earliest with minimally invasive procedures for prompt treatment of the case. Bronchoscopic lung cryobiopsy (BLC) is a newer interventional technique in pulmonary medicine for the diagnosis of mass lesions in the lung. Materials and methods This is a retrospective study of patients reporting to a tertiary care centre who were radiologically (by computed tomography scan of the chest) diagnosed with a mass lesion of the lung and who underwent BLC during the period from January 2018 to January 2021. We analysed the diagnostic yield of the technique defined as a positive tissue diagnosis after the histopathological examination (HPE) along with the safety of the procedure. Results During the above period, we evaluated 70 patients who were diagnosed radiologically with mass lesions of the lung and underwent BLC. We obtained tissue diagnoses for 66 cases and the result of four cases was inconclusive. The diagnostic yield of the BLC procedure was 94.29%. There was no mortality and complications were minimal bleeding and small pneumothorax. Conclusion BLC is a newer technique for obtaining lung tissue via a flexible bronchoscope obviating the need for open lung biopsy. The main advantage of the technique is providing larger tissue samples with minimal or no side effects without undergoing multiple procedures as compared to other bronchoscopic or surgical methods for obtaining a diagnosis from lung tissue. BLC is a safer and promising technique in diagnosing mass lesions of the lung with better yield.
肺部肿块是胸部放射学检查中常见的发现。由于需要考虑恶性肿瘤的可能性，肺部有肿块的患者预后难以预测。尽早通过微创程序诊断潜在病因以便及时治疗该病例至关重要。支气管镜下肺冷冻活检（BLC）是肺部医学中用于诊断肺部肿块的一种较新的介入技术。
这是一项对一家三级医疗中心报告的患者进行的回顾性研究，这些患者经胸部计算机断层扫描在放射学上被诊断为肺部肿块，并于2018年1月至2021年1月期间接受了BLC。我们分析了该技术的诊断率，定义为组织病理学检查（HPE）后阳性组织诊断结果，以及该程序的安全性。
在上述期间，我们评估了70例经放射学诊断为肺部肿块并接受BLC的患者。我们获得了66例的组织诊断结果，4例结果不确定。BLC程序的诊断率为94.29%。无死亡病例，并发症为少量出血和小气胸。
BLC是一种通过柔性支气管镜获取肺组织的新技术，无需进行开胸肺活检。与其他用于从肺组织获取诊断的支气管镜或手术方法相比，该技术的主要优点是提供更大的组织样本，副作用最小或无副作用，且无需进行多次程序。BLC是一种在诊断肺部肿块方面更安全且前景良好、诊断率更高的技术。
