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[Simple method of risk calculation in X-linked diseases].

作者信息

Jeanpierre M

出版信息

Ann Genet. 1987;30(1):17-21.

PMID:3498425
Abstract

The estimation of genetic risks in X-linked recessive disorders is a special case of Bayesian approach to probability calculation. Computing directly an estimation of the inverse of the risk is easier in this particular situation of only two mutually exclusive hypothesis: this function can be written in the form T = 1 + (To -1) X R, where R is a product of likehood ratios. The ratio of two probability density function represent a single factor, which is more manipulatable than the two components of the classical method.

摘要

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