Szentagothai János School of Ph.D Studies, Clinical Neurosciences, Semmelweis University, Budapest, Hungary.
Department of Behavioral Sciences, National Institute of Clinical Neurosciences, Semmelweis University, Budapest, Hungary.
Neurol Sci. 2022 Feb;43(2):927-937. doi: 10.1007/s10072-021-05857-0. Epub 2022 Jan 5.
Arousability and reactivity to sensory stimuli are essential features of sleep, discriminating it from coma and keeping the sleeper in contact with the environment. Arousals and oscillations during sleep serve the reversibility of sleep and carry an alarm function awakening the sleeper in danger. In this review, we will explore mechanisms and circuits involved in arousal intrusions within the sleep texture, focusing on the significance of these phenomena in two sleep-related conditions: NREM sleep parasomnias and sleep-related hypermotor epilepsy. Knowledges and gaps in the field are discussed.
觉醒性和对感觉刺激的反应是睡眠的基本特征，将其与昏迷区分开来，并使睡眠者与环境保持联系。睡眠中的觉醒和振荡有助于睡眠的可逆性，并具有警报功能，在睡眠者处于危险时唤醒他们。在这篇综述中，我们将探讨睡眠结构中觉醒侵入的相关机制和回路，重点关注这些现象在两种与睡眠相关的情况下的意义：非快速眼动期睡眠障碍和与睡眠相关的运动性癫痫。讨论了该领域的知识和差距。
