Yang Cheng-Xin, Lin Pei-Chin, Chang Chih-Chun, Tsai Huang-Wen, Sun Jen-Tang
Department of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei, Taiwan.
Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan.
Vox Sang. 2022 May;117(5):729-732. doi: 10.1111/vox.13238. Epub 2022 Jan 4.
An outbreak of coronavirus disease 2019 (COVID-19) occurred in mid-May of 2021 in Taiwan. After 2 months of hard work, transmissions were successfully prevented and the number of newly confirmed COVID-19 cases fell remarkably. We evaluated the impact of this outbreak on the massive transfusion protocol (MTP) in the emergency department (ED) of a trauma centre.
We retrospectively compared the activation and efficacy of MTP before, during and after the outbreak by analysing the clinical data relevant to MTP activations.
There was no remarkable change in the average number of MTP triggers per month during the outbreak. The interval from an MTP trigger to the first unit of blood transfused at bedside was significantly increased during the outbreak compared to that before the outbreak (22.4 min vs. 13.9 min, p < 0.001); while the 24-h survival rate decreased (57.1% vs. 71.1%, p = 0.938). There were no remarkable changes in blood unit return or wastage during the outbreak.
The COVID-19 outbreak limitedly affected MTP activation and waste of blood products, but significantly increased the interval from an MTP trigger to the first unit of blood transfused at bedside.
2021年5月中旬台湾地区发生了新型冠状病毒肺炎（COVID-19）疫情。经过两个月的艰苦努力，成功阻止了病毒传播，COVID-19新确诊病例数显著下降。我们评估了此次疫情对一家创伤中心急诊科大量输血方案（MTP）的影响。
通过分析与MTP启动相关的临床数据，回顾性比较疫情爆发前、爆发期间和爆发后MTP的启动情况及效果。
疫情爆发期间每月MTP启动的平均次数没有显著变化。与疫情爆发前相比，疫情爆发期间从MTP启动到床边首次输血的时间间隔显著延长（22.4分钟对13.9分钟，p<0.001）；而24小时生存率下降（57.1%对71.1%，p=0.938）。疫情爆发期间血液制品的回收或浪费情况没有显著变化。
COVID-19疫情对MTP的启动和血液制品的浪费影响有限，但显著延长了从MTP启动到床边首次输血的时间间隔。
