Xu Jing, Xue Bing, Li Lu, Qiao Jia, Redding Sharon R, Ouyang Yan-Qiong
School of Nursing, Wuhan University, Wuhan, China.
Global Health of Project HOPE, Washington, USA.
J Clin Nurs. 2023 May;32(9-10):2282-2297. doi: 10.1111/jocn.16194. Epub 2022 Jan 5.
To systematically evaluate the effectiveness of psychological interventions for women with breast cancer on sexual function, sexual satisfaction, sexual relationships, sexual distress and sexual quality of life.
Sexual dysfunction is common in women with breast cancer and seriously affects their quality of life and marital harmony. Several studies have explored the effects of psychological interventions related to sexual function of women with breast cancer, but results were inconclusive.
A systematic review and meta-analysis based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
A search of PubMed, EMBASE, PsycINFO, Web of Science, the Cochrane Library, Scopus, CINAHL, ProQuest Dissertations and Theses Global, ClinicalTrials.gov. and Open Grey was conducted from inception to 9 May 2021. Two reviewers independently screened studies, extracted data and conducted a quality appraisal of included studies using the Joanna Briggs Institute critical appraisal checklists.
Fifteen studies involving 1307 participants were included. The current study showed that psychological interventions made statistically significant improvements in sexual function (SMD = 0.82; 95% CI = [0.43, 1.20]; p < .001), sexual satisfaction (SMD = 0.95; 95% CI = [0.19, 1.72]; p = .01), sexual relationships (SMD = 0.37; 95% CI = [0.15, 0.60]; p = .001) and sexual distress (MD = -5.05; 95% CI = [-7.88, -2.22]; p = .0005) of women with breast cancer. A subgroup analysis regarding the types of psychological interventions indicated that cognitive behavioural therapy and psychoeducational therapy were beneficial to sexual function and satisfaction, and psychosexual counselling could also improve sexual function.
Psychological interventions, especially psychoeducational therapy and cognitive behavioural therapy, are effective for improving the sexual health of women with breast cancer.
This current study provides evidence for the application of psychosexual interventions in women with breast cancer.
The study has been registered on the PROSPERO on 6 June 2021, with the registration number CRD42021253493.
系统评价针对乳腺癌女性的心理干预对性功能、性满意度、性关系、性困扰及性生活质量的有效性。
性功能障碍在乳腺癌女性中很常见，严重影响她们的生活质量和婚姻和谐。多项研究探讨了与乳腺癌女性性功能相关的心理干预效果，但结果尚无定论。
基于系统评价与Meta分析的首选报告项目（PRISMA）指南进行系统评价和Meta分析。
检索了PubMed、EMBASE、PsycINFO、科学引文索引、考科蓝图书馆、Scopus、护理学与健康领域数据库、ProQuest全球博硕士论文数据库、ClinicalTrials.gov和Open Grey，检索时间从建库至2021年5月9日。两名研究者独立筛选研究、提取数据，并使用乔安娜·布里格斯循证卫生保健中心的批判性评价清单对纳入研究进行质量评估。
纳入15项研究，共1307名参与者。本研究表明，心理干预使乳腺癌女性的性功能（标准化均数差=0.82；95%可信区间=[0.43, 1.20]；p<0.001）、性满意度（标准化均数差=0.95；95%可信区间=[0.19, 1.72]；p=0.01）、性关系（标准化均数差=0.37；95%可信区间=[0.15, 0.60]；p=0.001）和性困扰（均数差=-5.05；95%可信区间=[-7.88, -2.22]；p=0.0005）在统计学上有显著改善。关于心理干预类型的亚组分析表明，认知行为疗法和心理教育疗法对性功能和满意度有益，性心理咨询也可改善性功能。
心理干预，尤其是心理教育疗法和认知行为疗法，对改善乳腺癌女性的性健康有效。
本研究为性心理干预在乳腺癌女性中的应用提供了证据。
本研究于2021年6月6日在国际前瞻性系统评价注册库PROSPERO上注册，注册号为CRD42021253493。
