Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Dr, Ste 401, Boston, MA, 02215, USA.
AIDS Behav. 2022 Jul;26(7):2212-2223. doi: 10.1007/s10461-021-03571-8. Epub 2022 Jan 5.
In a nationwide sample of Black women in the U.S., we assessed preferences for HIV preexposure prophylaxis (PrEP) products, including long-acting injectable (LAI) PrEP and once-daily oral PrEP. Among 315 respondents, 32.1% were aware of PrEP and 40.6% were interested in using it; interest increased to 62.2% if PrEP were provided for free. Oral PrEP was the preferred option (51.1%), followed by LAI PrEP (25.7%), vaginal gel (16.5%), and vaginal ring (6.7%). When examining oral and LAI PrEP alone, most (62.7%) preferred oral PrEP. LAI PrEP was more likely to be preferred among respondents with concerns about healthcare costs or PrEP-related stigma, and among those who reported inconsistent condom use and multiple sexual partners. Although most Black women preferred oral PrEP, LAI PrEP may be appealing to a subset with social and structural barriers to PrEP use, such as cost and stigma, and those at increased risk of HIV infection.
在美国的一项全国性黑人女性样本研究中，我们评估了对 HIV 暴露前预防（PrEP）产品的偏好，包括长效注射（LAI）PrEP 和每日口服 PrEP。在 315 名受访者中，32.1%的人了解 PrEP，40.6%的人有兴趣使用它；如果免费提供 PrEP，兴趣增加到 62.2%。口服 PrEP 是首选（51.1%），其次是 LAI PrEP（25.7%）、阴道凝胶（16.5%）和阴道环（6.7%）。当单独检查口服和 LAI PrEP 时，大多数（62.7%）更喜欢口服 PrEP。对于那些担心医疗保健费用或与 PrEP 相关耻辱感的受访者，以及那些报告避孕套使用不一致和多个性伴侣的受访者，LAI PrEP 更有可能受到青睐。尽管大多数黑人女性更喜欢口服 PrEP，但 LAI PrEP 可能对那些存在 PrEP 使用障碍（如成本和耻辱感）以及 HIV 感染风险增加的人群具有吸引力。
