Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco A. C. Subsede Noreste, 66629 Apodaca- 66629, Nuevo León, México.
Departamento de Ciencias Químico Biológicas, Instituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez-32310, Chihuahua, México.
Curr Top Med Chem. 2022;22(2):150-167. doi: 10.2174/1568026622666220105104355.
The pecan nutshell contains phytochemicals with various biological activities that are potentially useful in the prevention or treatment of diseases, such as cancer, diabetes, and metabolic imbalances associated with heart diseases.
The aim of this study is to update this topic by means of a literature review and include those studies that contribute to the knowledge of the chemical composition and biological activities of pecan nutshell, particularly those related to the therapeutic potential against some chronic degenerative diseases associated with oxidative stress.
Exhaustive and detailed review of the existing literature was conducted using electronic databases.
The pecan nutshell is a promising natural product with pharmaceutical uses in various diseases. However, additional research related to the assessment of efficient extraction methods and characterization, particularly the evaluation of the mechanisms of action in new in vivo models, is necessary to confirm these findings and development of new drugs with therapeutic use.
山核桃壳含有具有各种生物活性的植物化学成分，这些成分在预防或治疗疾病方面可能具有潜在的用途，如癌症、糖尿病和与心脏病相关的代谢失衡。
本研究旨在通过文献综述更新这一主题，并纳入那些有助于了解山核桃壳的化学成分和生物活性的研究，特别是那些与针对某些与氧化应激相关的慢性退行性疾病的治疗潜力相关的研究。
使用电子数据库进行了全面而详细的文献综述。
山核桃壳是一种很有前途的天然产物，在各种疾病的药物治疗中有应用潜力。然而，还需要进行更多与评估有效提取方法和特性相关的研究，特别是在新的体内模型中评估作用机制的研究，以证实这些发现，并开发具有治疗用途的新药。
