Acinapura A J, Rose D M, Kramer M D, Jacobowitz I J, Cunningham J N
Department of Thoracic Surgery, St. Vincent's Hospital and Medical Center, New York, New York.
J Cardiovasc Surg (Torino). 1987 Sep-Oct;28(5):552-7.
It is well recognized that patients with abdominal aortic aneurysms have a high incidence of coronary artery disease, and that the major cause of death in patients undergoing aneurysmectomy has been acute myocardial infarction. In order to assess the incidence of significant coronary artery disease, cardiac catheterization was performed on 42 consecutive patients with abdominal aortic aneurysms. Thirty-six patients (85.7%) had significant anatomic coronary artery disease. Interestingly, all 8 patients with ejection fractions of less than 50% had triple vessel disease or left main disease, and 12 of 34 patients with ejection fractions greater than or equal to 50% had triple vessel disease or left main disease. Of the 30 patients who were NYHA Class I or Class II, 14 (46.7%) had triple vessel disease or left main disease. All 20 patients with triple vessel disease or left main disease underwent myocardial revascularization 7 to 10 days prior to abdominal aneurysmectomy. No patients had a perioperative myocardial infarction either following coronary artery bypass surgery or abdominal aortic aneurysm resection, and there were no operative mortalities. Although this was not a randomized study, it would seem from these results that in selected patients, myocardial revascularization prior to abdominal aneurysmectomy can decrease the incidence of acute myocardial infarction and also decrease operative mortality. It is presently recommended that all symptomatic patients, patients with ejection fractions of less than 50%, and asymptomatic patients with ejection fractions of greater than or equal to 50% with positive exercise radionuclide angiography undergo cardiac catheterization prior to aneurysmectomy, and those patients with left main disease or severe coronary artery disease undergo myocardial revascularization prior to aneurysm resection.
众所周知,腹主动脉瘤患者冠心病发病率很高,并且接受动脉瘤切除术患者的主要死亡原因一直是急性心肌梗死。为了评估严重冠心病的发病率,对42例连续性腹主动脉瘤患者进行了心导管检查。36例患者(85.7%)有严重的解剖学冠状动脉疾病。有趣的是,所有8例射血分数低于50%的患者均有三支血管病变或左主干病变,34例射血分数大于或等于50%的患者中有12例有三支血管病变或左主干病变。在纽约心脏协会心功能I级或II级的30例患者中,14例(46.7%)有三支血管病变或左主干病变。所有20例有三支血管病变或左主干病变的患者在腹主动脉瘤切除术前行心肌血运重建术7至10天。冠状动脉搭桥手术或腹主动脉瘤切除术后均无患者发生围手术期心肌梗死,也无手术死亡病例。虽然这不是一项随机研究,但从这些结果来看,在特定患者中,腹主动脉瘤切除术前行心肌血运重建术可降低急性心肌梗死的发生率,并降低手术死亡率。目前建议,所有有症状的患者、射血分数低于50%的患者以及运动放射性核素血管造影阳性的无症状射血分数大于或等于50%的患者在动脉瘤切除术前行心导管检查,而那些有左主干病变或严重冠状动脉疾病的患者在动脉瘤切除术前进行心肌血运重建术。