Ito Yu, Miyoshi Ai, Ueda Yutaka, Tanaka Yusuke, Nakae Ruriko, Morimoto Akiko, Shiomi Mayu, Enomoto Takayuki, Sekine Masayuki, Sasagawa Toshiyuki, Yoshino Kiyoshi, Harada Hiroshi, Nakamura Takafumi, Murata Takuya, Hiramatsu Keizo, Saito Junko, Yagi Junko, Tanaka Yoshiaki, Kimura Tadashi
Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka 567-0871, Japan.
Department of Obstetrics and Gynecology, Niigata University Graduate School of Medicine, Chuo-ku, Niigata 951-8520, Japan.
Mol Clin Oncol. 2022 Feb;16(2):27. doi: 10.3892/mco.2021.2460. Epub 2021 Dec 8.
The present study created an artificial intelligence (AI)-automated diagnostics system for uterine cervical lesions and assessed the performance of these images for AI diagnostic imaging of pathological cervical lesions. A total of 463 colposcopic images were analyzed. The traditional colposcopy diagnoses were compared to those obtained by AI image diagnosis. Next, 100 images were presented to a panel of 32 gynecologists who independently examined each image in a blinded fashion and diagnosed them for four categories of tumors. Then, the 32 gynecologists revisited their diagnosis for each image after being informed of the AI diagnosis. The present study assessed any changes in physician diagnosis and the accuracy of AI-image-assisted diagnosis (AISD). The accuracy of AI was 57.8% for normal, 35.4% for cervical intraepithelial neoplasia (CIN)1, 40.5% for CIN2-3 and 44.2% for invasive cancer. The accuracy of gynecologist diagnoses from cervical pathological images, before knowing the AI image diagnosis, was 54.4% for CIN2-3 and 38.9% for invasive cancer. After learning of the AISD, their accuracy improved to 58.0% for CIN2-3 and 48.5% for invasive cancer. AI-assisted image diagnosis was able to improve gynecologist diagnosis accuracy significantly (P<0.01) for invasive cancer and tended to improve their accuracy for CIN2-3 (P=0.14).
本研究创建了一个用于子宫颈病变的人工智能(AI)自动诊断系统,并评估了这些图像在子宫颈病变AI诊断成像中的性能。共分析了463张阴道镜图像。将传统阴道镜诊断结果与AI图像诊断结果进行比较。接下来,向由32名妇科医生组成的小组展示了100张图像,这些医生以盲法独立检查每张图像,并对四类肿瘤进行诊断。然后,32名妇科医生在得知AI诊断结果后,重新审视了他们对每张图像的诊断。本研究评估了医生诊断的任何变化以及AI图像辅助诊断(AISD)的准确性。AI对正常情况的诊断准确率为57.8%,对宫颈上皮内瘤变(CIN)1为35.4%,对CIN2 - 3为40.5%,对浸润癌为44.2%。在不知道AI图像诊断结果的情况下,妇科医生从宫颈病理图像中做出诊断的准确率,对于CIN2 - 3为54.4%,对于浸润癌为38.9%。在得知AISD后,他们对CIN2 - 3的诊断准确率提高到58.0%,对浸润癌的诊断准确率提高到48.5%。AI辅助图像诊断能够显著提高妇科医生对浸润癌的诊断准确率(P<0.01),并且对于CIN2 - 3有提高其诊断准确率的趋势(P = 0.14)。