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为应对中国糖尿病患病率上升的问题,肥胖问题亟待解决——2003年至2009年的时间变化情况。

Obesity needs to be addressed to tackle the increased prevalence of diabetes in China - Temporal changes from 2003 to 2009.

作者信息

Pardhan Shahina, Zheng Dingchang, Chen Zhiqing, López Sánchez Guillermo F

机构信息

Vision and Eye Research Institute, School of Medicine, Faculty of Health, Education, Medicine and Social Care, Anglia Ruskin University, Cambridge CB1 1PT, United Kingdom.

Faculty of Health and Life Sciences, University of Coventry, Coventry, United Kingdom.

出版信息

Prev Med Rep. 2021 Oct 25;24:101625. doi: 10.1016/j.pmedr.2021.101625. eCollection 2021 Dec.

Abstract

This study aimed to analyse the temporal change of diabetes and any associated risk and protective factors for diabetes in Chinese adults between Wave 0 (2003) and Wave 1 (2009) of the World Health Organization (WHO) Study on global AGEing and adult health (SAGE). Data from China of the SAGE were analysed. Diabetes (outcome variable) was assessed by the yes/no question: "Have you ever been diagnosed with diabetes (high blood sugar)?". Exposure variables examined in bivariate and multivariate multiple regression included sex, age, marital status, education, smoking, alcohol, fruit and vegetables consumption, physical activity and body mass index (BMI). Significant exposure variables in bivariate analyses were included in multivariate analyses (2003: age and tobacco; 2009: age, BMI, education and alcohol). In Wave 0 (2003), there were 3993 Chinese adults, of which 67 (1.7%) self-reported to have diabetes. In Wave 1 (2009), there were a total of 9524 Chinese adults, of which 770 (8.1%) had diabetes. The overall prevalence of diabetes in Chinese adults increased by 4.76 times between the two timeframes (1.7%, age range 27-84 years, average age 58.51 ± 12.70 years, 59.70% females in 2003 to 8.1%, age range 20-95 years, average age 65.31 ± 10.19 years, 53.64% females in 2009). Multivariate regression retained older age ≥ 60 years (OR 4.34, 95% CI 2.67-7.07) as the main risk factor in 2003 data, while in 2009 the odds ratio for older age ≥ 60 years decreased (OR 2.45, 95% CI 2.06-2.92), but included a significant association of obesity (OR 2.11, 95% CI 1.60-2.78) and excess weight (OR 1.42, 95% CI 1.19-1.69). The significant association with excess weight and obesity associated with the increased prevalence of diabetes in 2009 is a cause of concern and should be addressed by public health strategies in China.

摘要

本研究旨在分析世界卫生组织(WHO)全球老龄化与成人健康研究(SAGE)第0轮(2003年)和第1轮(2009年)之间中国成年人糖尿病的时间变化以及糖尿病的任何相关风险和保护因素。对SAGE中国部分的数据进行了分析。糖尿病(结果变量)通过“是/否”问题进行评估:“你是否曾被诊断患有糖尿病(血糖高)?”。在双变量和多变量多元回归中检验的暴露变量包括性别、年龄、婚姻状况、教育程度、吸烟、饮酒、水果和蔬菜摄入量、身体活动以及体重指数(BMI)。双变量分析中的显著暴露变量被纳入多变量分析(2003年:年龄和烟草;2009年:年龄、BMI、教育程度和饮酒)。在第0轮(2003年),有3993名中国成年人,其中67人(1.7%)自我报告患有糖尿病。在第1轮(2009年),共有9524名中国成年人,其中770人(8.1%)患有糖尿病。在这两个时间框架之间,中国成年人糖尿病的总体患病率增加了4.76倍(2003年为1.7%,年龄范围27 - 84岁,平均年龄58.51±12.70岁,女性占59.70%;2009年为8.1%,年龄范围20 - 95岁,平均年龄65.31±10.19岁,女性占53.64%)。多变量回归显示,在2003年的数据中,年龄≥60岁(比值比4.34,95%置信区间2.67 - 7.07)是主要风险因素,而在2009年,年龄≥60岁的比值比有所下降(比值比2.45,95%置信区间2.06 - 2.92),但包括肥胖(比值比2.11,95%置信区间1.60 - 2.78)和超重(比值比1.42,95%置信区间1.19 - 1.69)的显著关联。2009年超重和肥胖与糖尿病患病率增加之间的显著关联令人担忧,中国的公共卫生策略应予以应对。

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