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[应用单克隆抗体分析布鲁氏菌病患者的淋巴细胞群体及T淋巴细胞亚群]

[Lymphocyte population and T lymphocyte subsets in brucellosis analyzed by monoclonal antibodies].

作者信息

Koçoğlu T, Kansu E, Gülmezoğlu E, Akalin E

机构信息

Hacettepe Universitesi, Tip Fakültesi, Mikrobiyoloji Anabilim Dali Uzman Doktoru.

出版信息

Mikrobiyol Bul. 1986 Oct;20(4):221-9.

PMID:3498876
Abstract

In this study, T-lymphocyte subsets and HLA-DR antigen (+) cells in the peripheral blood of 19 patients with acute brucellosis were determined and the results were compared to 19 healthy control subjects. Our findings suggest that exposure of the immune system to brucella microorganism and related antigens results in an increase in the circulating "activated" cell numbers (HLA-DR+) without significant alterations in the subpopulations of peripheral blood lymphocytes.

摘要

在本研究中,测定了19例急性布鲁氏菌病患者外周血中的T淋巴细胞亚群和HLA - DR抗原(+)细胞,并将结果与19名健康对照者进行比较。我们的研究结果表明,免疫系统暴露于布鲁氏菌微生物和相关抗原会导致循环中“活化”细胞数量(HLA - DR +)增加,而外周血淋巴细胞亚群无明显变化。

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