恶性疟原虫相关性急性肾损伤伴多发性神经病和动脉内血栓形成（中风）。
Falciparum malaria associated acute kidney injury with polyneuropathy and intra-arterial thrombosis (stroke).
机构信息
Sindh Institute of Urology and Transplant, Karachi, Sindh, Pakistan.
出版信息
Eur J Med Res. 2022 Jan 6;27(1):2. doi: 10.1186/s40001-021-00627-2.
BACKGROUND
Malaria is still major problem in developing countries, such as Pakistan. Besides fever, body ache and vomiting it can present with acute kidney injury, proteinuria, hematuria and cerebral manifestations which are more common with falciparum malaria. Neurological manifestations are rare presentation of malaria and should be consider in patients who are admitting with features of neuropathy and stroke.
CASE PRESENTATION
We describe an unusual case of falciparum malaria, complicated by acute kidney injury who developed Polyneuropathy and intra-arterial thrombosis in middle cerebral artery territory. Our patient recovered his renal functions during admission and recovered his power and sensation in his limbs as well after 1 month.
CONCLUSION
Malaria cause neurological manifestations including axonal and sensory neuropathy, cerebral venous and arterial thrombosis, PMNS, cerebellar signs and symptoms, psychosis, etc. With prompt diagnosis and early treatment they can be cure and regain their motor and sensory functions to normal level.
背景
疟疾仍然是发展中国家（如巴基斯坦）的一个主要问题。除了发热、身体疼痛和呕吐外，它还可能导致急性肾损伤、蛋白尿、血尿和脑部表现，而这些表现在恶性疟原虫疟疾中更为常见。神经表现是疟疾的罕见表现，对于以神经病和中风特征入院的患者，应考虑这种表现。
病例介绍
我们描述了一例不常见的恶性疟原虫疟疾病例，并发急性肾损伤，导致大脑中动脉区域多发性神经病和动脉内血栓形成。我们的患者在住院期间恢复了肾功能，在 1 个月后恢复了四肢的力量和感觉。
结论
疟疾可引起包括轴索性和感觉性神经病、脑静脉和动脉血栓形成、PMNS、小脑征和症状、精神病等在内的神经表现。通过及时诊断和早期治疗，它们可以治愈并恢复到正常的运动和感觉功能水平。
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