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遵守关于有创通气早期撤机的质量指标是否能改善经济结果?一项单中心回顾性研究。

Does adherence to a quality indicator regarding early weaning from invasive ventilation improve economic outcome? A single-centre retrospective study.

作者信息

Zuber Alexander, Kumpf Oliver, Spies Claudia, Höft Moritz, Deffland Marc, Ahlborn Robert, Kruppa Jochen, Jochem Roland, Balzer Felix

机构信息

Institute of Medical Informatics, Charité Universitätsmedizin Berlin, Berlin, Germany.

Department of Anesthesiology and Operative Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.

出版信息

BMJ Open. 2022 Jan 6;12(1):e045327. doi: 10.1136/bmjopen-2020-045327.

Abstract

OBJECTIVES

To measure and assess the economic impact of adherence to a single quality indicator (QI) regarding weaning from invasive ventilation.

DESIGN

Retrospective observational single-centre study, based on electronic medical and administrative records.

SETTING

Intensive care unit (ICU) of a German university hospital, reference centre for acute respiratory distress syndrome.

PARTICIPANTS

Records of 3063 consecutive mechanically ventilated patients admitted to the ICU between 2012 and 2017 were extracted, of whom 583 were eligible adults for further analysis. Patients' weaning protocols were evaluated for daily adherence to quality standards until ICU discharge. Patients with <65% compliance were assigned to the low adherence group (LAG), patients with ≥65% to the high adherence group (HAG).

PRIMARY AND SECONDARY OUTCOME MEASURES

Economic healthcare costs, clinical outcomes and patients' characteristics.

RESULTS

The LAG consisted of 378 patients with a median negative economic results of -€3969, HAG of 205 (-€1030), respectively (p<0.001). Median duration of ventilation was 476 (248; 769) hours in the LAG and 389 (247; 608) hours in the HAG (p<0.001). Length of stay (LOS) in the LAG on ICU was 21 (12; 35) days and 16 (11; 25) days in the HAG (p<0.001). LOS in the hospital was 36 (22; 61) days in the LAG, and within the HAG, respectively, 26 (18; 48) days (p=0.001).

CONCLUSIONS

High adherence to this single QI is associated with better clinical outcome and improved economic returns. Therefore, the results support the adherence to QI. However, the examined QI does not influence economic outcome as the decisive factor.

摘要

目的

衡量并评估遵守一项关于有创通气撤机的质量指标(QI)的经济影响。

设计

基于电子医疗和行政记录的回顾性观察单中心研究。

地点

德国一家大学医院的重症监护病房(ICU),急性呼吸窘迫综合征参考中心。

参与者

提取了2012年至2017年间连续入住该ICU的3063例机械通气患者的记录,其中583例符合条件的成年患者可进行进一步分析。评估患者的撤机方案每日对质量标准的遵守情况,直至患者从ICU出院。依从性低于65%的患者被分配到低依从性组(LAG),依从性≥65%的患者被分配到高依从性组(HAG)。

主要和次要结局指标

医疗保健经济成本、临床结局和患者特征。

结果

低依从性组包括378例患者,经济结果中位数为-3969欧元,高依从性组为205例(-1030欧元)(p<0.001)。低依从性组通气的中位数时长为476(248;769)小时,高依从性组为389(247;608)小时(p<0.001)。低依从性组在ICU的住院时长为21(12;35)天,高依从性组为16(11;25)天(p<0.001)。低依从性组在医院的住院时长为36(22;61)天,高依从性组为26(18;48)天(p=0.001)。

结论

高度遵守这一单一质量指标与更好的临床结局和更高的经济回报相关。因此,研究结果支持遵守质量指标。然而,所检查的质量指标并非影响经济结局的决定性因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfb/8739420/e66538d73d28/bmjopen-2020-045327f01.jpg

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