Murase K, Ishine M, Kataoka M, Itoh H, Mogami H, Iio A, Hamamoto K
Department of Radiology, Ehime University School of Medicine, Japan.
Eur J Nucl Med. 1987;13(5):244-9. doi: 10.1007/BF00252601.
The effect of respiratory motion on the image quality of single photon emission computed tomography (SPECT) was investigated by computer simulation and experimentation. In the computer simulation, the phantom was assumed to be cylindrical with a uniform background and a spherical cold or hot spot. To simulate respiratory motion, a cyclic linear motion parallel to the axis of rotation of a gamma camera was assumed. The contrast in the transaxial images was calculated for various respiratory amplitudes and its dependence on lesion size and object contrast was investigated. In the experiments, a moving phantom was used to simulate respiratory motion. The simulation and the experimental results were in good agreement within the range of statistical error. The effect on the lesion detectability was investigated using receiver operating characteristics (ROC) analysis, and a method for correcting respiratory motion was devised.
通过计算机模拟和实验研究了呼吸运动对单光子发射计算机断层扫描（SPECT）图像质量的影响。在计算机模拟中，假定体模为圆柱形，具有均匀背景和球形冷区或热区。为了模拟呼吸运动，假定有一个平行于伽马相机旋转轴的循环线性运动。计算了不同呼吸幅度下横断面图像中的对比度，并研究了其对病变大小和物体对比度的依赖性。在实验中，使用了一个移动体模来模拟呼吸运动。在统计误差范围内，模拟结果与实验结果吻合良好。使用接收者操作特征（ROC）分析研究了对病变可检测性的影响，并设计了一种校正呼吸运动的方法。
