接受睾酮治疗的跨性别青少年男性与体重指数匹配的顺性别女性的心脏代谢参数。
Cardiometabolic Parameters Among Transgender Adolescent Males on Testosterone Therapy and Body Mass Index-Matched Cisgender Females.
作者信息
Valentine Anna, Nokoff Natalie, Bonny Andrea, Chelvakumar Gayathri, Indyk Justin, Leibowitz Scott, Nahata Leena
机构信息
Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio, USA.
Department of Pediatrics, Division of Endocrinology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.
出版信息
Transgend Health. 2021 Dec 2;6(6):369-373. doi: 10.1089/trgh.2020.0052. eCollection 2021 Dec.
Abstract
Limited data are available on changes in metabolic parameters in transgender youth on testosterone therapy in comparison with cisgender females. Data from 42 transgender males on testosterone therapy were retrospectively analyzed. Body mass index (BMI) and lipid profile changes were compared with BMI-matched females. There was a significant increase in BMI over time in the transgender males as compared with the cisgender females, and a decrease in high-density lipoprotein in the transgender males after starting testosterone therapy. Longitudinal prospective studies with cisgender controls are needed to better define effects of testosterone therapy in adolescents.
摘要
与顺性别女性相比，关于接受睾酮治疗的跨性别青少年代谢参数变化的数据有限。对42名接受睾酮治疗的跨性别男性的数据进行了回顾性分析。将体重指数（BMI）和血脂谱变化与BMI匹配的女性进行了比较。与顺性别女性相比，跨性别男性的BMI随时间显著增加，且开始睾酮治疗后跨性别男性的高密度脂蛋白降低。需要开展有顺性别对照的纵向前瞻性研究，以更好地确定睾酮治疗对青少年的影响。
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