Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA.
Neurosurgery. 2022 Feb 1;90(2):215-220. doi: 10.1227/NEU.0000000000001782.
Previous studies have examined the impact of preoperative duration of symptoms (DOS) on lumbar spinal surgery outcomes although this has not been explored for anterior lumbar interbody fusion (ALIF).
To assess the impact of preoperative DOS on patient-reported outcome measures (PROMs) of ALIF with posterior instrumentation.
A database was retrospectively reviewed for ALIFs with posterior instrumentation. PROMs recorded at preoperative, 6-wk, 12-wk, 6-mo, and 1-yr postoperative timepoints included Visual Analog Scale back and leg, Oswestry Disability Index, 12-Item Short-Form Physical Component Score (SF-12 PCS), and PROM Information System physical function. Achievement of minimum clinically important difference (MCID) was determined by comparing differences in postoperative PROMs from baseline to established values. Patients were grouped based on preoperative DOS into <1-yr and ≥1-yr groups. Differences in PROMs were compared using a t-test, whereas MCID achievement used a χ2 test.
Fifty-three patients were included, with 20 in the <1-yr group and 33 in the ≥1-yr group. The most common diagnosis was isthmic spondylolisthesis. No significant preoperative differences were observed in any PROM. DOS groups demonstrated significantly different scores for SF-12 PCS at 6 wk (P = .049). No significant differences in MCID achievement were observed between groups for any PROM.
ALIF patients demonstrated similar levels of pain, disability, and physical function regardless of preoperative DOS, except for back pain and physical function at intermittent timepoints. MCID achievement did not differ based on DOS for all outcome measures.
尽管尚未探讨前路腰椎间融合术(ALIF)的术前症状持续时间(DOS)对其手术结果的影响,但先前的研究已经研究了其对腰椎脊柱手术结果的影响。
评估术前 DOS 对后路器械固定 ALIF 患者报告的结果测量(PROM)的影响。
回顾性地对后路器械固定的 ALIF 进行了数据库检索。记录了术前、6 周、12 周、6 个月和 1 年的 PROM,包括视觉模拟量表(VAS)腰背、Oswestry 残疾指数、12 项简短健康调查问卷物理成分评分(SF-12 PCS)和 PROM 信息系统的身体功能。通过将术后 PROM 与既定值相比,确定了最小临床重要差异(MCID)的实现。根据术前 DOS 将患者分为<1 年和≥1 年组。使用 t 检验比较 PROM 的差异,而使用 χ2 检验比较 MCID 的实现。
共纳入 53 例患者,其中<1 年组 20 例,≥1 年组 33 例。最常见的诊断是峡部裂性脊椎滑脱症。在任何 PROM 中均未观察到术前有明显差异。在 6 周时,SF-12 PCS 评分在 DOS 组之间存在显著差异(P=0.049)。在任何 PROM 中,两组之间 MCID 实现的差异均无统计学意义。
ALIF 患者无论术前 DOS 如何,疼痛、残疾和身体功能的水平均相似,但在间歇性时间点时腰背疼痛和身体功能除外。基于所有结果测量,DOS 并未导致 MCID 实现的差异。