Huaux J P, Esselinckx W, Meunier H, Dufour J P, Devogelaer J P, Nagant de Deuxchaisnes C
Service de Rhumatologie, Cliniques Universitaires Saint-Luc, Bruxelles, Belgique.
Rev Rhum Mal Osteoartic. 1987 Jul-Sep;54(7-9):549-53.
The authors briefly summarize 16 cases involving digital necrosis observed in the course of rheumatic disorders (3 carpal tunnel syndromes, 2 cases of panarteritis, 2 of rheumatoid arthritis, 2 of lupus erythematosus, 2 of scleroderma, 2 of dermatomyositis, 1 of adult form of Still's disease, 1 of gout, and 1 case of cryoglobulinemia). In addition the case reports of 129 patients with connective tissue disease were reviewed (74 cases of disseminated lupus erythematosus, 43 of scleroderma, and 12 mixed connective tissue disorders). Soft tissue destruction of digits was observed in 15, 39 and 25% of these patients respectively, and true tissue necrosis of varying extent in 7, 9 and 0% of these cases. The incidence and pathogenic mechanisms responsible for these disorders and lesions were discussed.
作者简要总结了16例在风湿性疾病过程中观察到的指端坏死病例（3例腕管综合征、2例结节性多动脉炎、2例类风湿关节炎、2例红斑狼疮、2例硬皮病、2例皮肌炎、1例成人斯蒂尔病、1例痛风和1例冷球蛋白血症）。此外，还回顾了129例结缔组织病患者的病例报告（74例播散性红斑狼疮、43例硬皮病和12例混合性结缔组织病）。在这些患者中，分别有15%、39%和25%观察到手指软组织破坏，在这些病例中，分别有7%、9%和0%观察到不同程度的真正组织坏死。讨论了这些疾病和病变的发病率及致病机制。
