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钝性肾损伤后的晚期并发症:一项法国多中心研究

[Late complications after blunt renal trauma: A French multicenter study].

作者信息

Brenot G, Dominique I, Peyronnet B, Savoie P H, Chiron P

机构信息

Hôpital d'instruction des armées Bégin, Saint-Mandé, France.

Hôpital des Diaconesses, Paris, France.

出版信息

Prog Urol. 2022 Apr;32(5):363-372. doi: 10.1016/j.purol.2021.12.002. Epub 2022 Jan 6.

Abstract

INTRODUCTION

Among genitourinary traumas, blunt trauma to the kidney are the most frequent: their initial management has been well studied but their development at a distance is poorly documented. The objective of this study was to assess the late complications of blunt renal trauma, and to investigate their predictive factors for occurrence.

MATERIALS AND METHODS

A retrospective observational study of the TraumAFUF project was conducted, including, between 2005 and 2018, all blunt renal trauma treated in 18 French hospitals and followed for more than 3 months. The characteristics of the initial trauma, as well as any complications occurring after three months, were identified. The patients were divided into two groups: onset of a late complication (LC) or uncomplicated (UC). The groups were compared in univariate and multivariate analyses to identify the risk factors for the occurrence of these complications.

RESULTS

Among the 454 patients included, 50 presented with LC (11%), as symptomatic morphologically altered kidney (2.9%), secondarily impaired biological renal function (2.9%), or secondary arterial hypertension (2.4%). The risk factors identified were, during initial medical care, a high-grade renal trauma≥IV (OR=2.4, P=0.025), active bleeding (OR=2.6, P=0.007), the need for transfusion (OR=2.3, P=0.001), or interventional (R=1.7, P=0.09) or endoscopic treatment (OR=2.0, P=0.035).

CONCLUSION

In this study, late complications occurred in 11% of cases after blunt renal trauma. The risk factors identified make it possible to draw up a patient profile who would benefit from prolonged follow-up to detect these complications.

摘要

引言

在泌尿生殖系统创伤中,肾脏钝性创伤最为常见:其初始处理已得到充分研究,但远期发展情况记录较少。本研究的目的是评估肾脏钝性创伤的晚期并发症,并探究其发生的预测因素。

材料与方法

对TraumAFUF项目进行回顾性观察研究,纳入2005年至2018年间在18家法国医院接受治疗且随访超过3个月的所有肾脏钝性创伤患者。确定初始创伤的特征以及3个月后出现的任何并发症。将患者分为两组:发生晚期并发症(LC)组和未发生并发症(UC)组。对两组进行单因素和多因素分析,以确定这些并发症发生的危险因素。

结果

在纳入的454例患者中,50例出现LC(11%),表现为有症状的形态改变的肾脏(2.9%)、继发性肾功能受损(2.9%)或继发性动脉高血压(2.4%)。确定的危险因素包括在初始医疗护理期间,高级别肾脏创伤≥IV级(OR = 2.4,P = 0.025)、活动性出血(OR = 2.6,P = 0.007)、需要输血(OR = 2.3,P = 0.001),或介入治疗(R = 1.7,P = 0.09)或内镜治疗(OR = 2.0,P = 0.035)。

结论

在本研究中,肾脏钝性创伤后11%的病例发生了晚期并发症。所确定的危险因素使得能够勾勒出可能受益于延长随访以检测这些并发症的患者特征。

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