Department of General Surgery, Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, New York, NY.
Department of General Surgery, Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, New York, NY.
J Vasc Surg. 2022 Jul;76(1):132-140. doi: 10.1016/j.jvs.2021.12.062. Epub 2022 Jan 6.
Aneurysmal extension of abdominal aortic aneurysms (AAAs) to the common iliac artery (CIA) presents a technical challenge to successful endovascular abdominal aortic aneurysm repair (EVAR). In the present study, we compared sac shrinkage and perioperative outcomes after the bell-bottom technique (BBT), internal iliac artery embolization and external iliac artery extension (EIE), and iliac branch endoprosthesis (IBE).
Using the Vascular Quality Initiative database, a retrospective analysis was conducted for patients who had undergone EVAR from 2013 to 2019. The demographic, anatomic, and perioperative data were analyzed. All patients with a proximal aortic neck length <10 mm and aortic graft diameter >32 mm were excluded from the analysis. The patients were subdivided into four groups according to the distal limb strategy: group 1, control group with a bilateral common iliac artery limb <20 mm; group 2, BBT with either a unilateral or bilateral limb >20 mm; group 3, EIE technique; and group 4, IBE. The primary endpoint was the maximal change in the aortic diameter during follow-up. The secondary endpoints included postoperative complications and the rate of endoleak.
The records for 14,455 patients who had undergone EVAR were queried and 5788 met the anatomic criteria. The average age was 73 years, and 86.3% were men. The maximal change in the aortic diameter in the control, BBT, IBE, and EIE groups was -7.2 mm, -6.1 mm, -4.6 mm, and -6.8 mm, respectively (P = .06). The differences were not statistically significant on univariate analysis at an average follow-up of 405 days. However, on multivariable analysis (P = .01), compared with the control group, the BBT and IBE groups were 18.4% (odds ratio [OR], 0.816; 95% confidence interval [CI], 0.68-0.98) and 48.0% (OR, 0.52; 95% CI, 0.33-0.82) less likely to experience aneurysmal shrinkage, respectively. In contrast, the EIE group showed no significant difference in shrinkage compared with that in the control group. Multivariable analysis of the groups also revealed that compared directly with the BBT group, the EIE group was 69.5% more likely to have experienced shrinkage in the aortic aneurysmal diameter (OR, 1.70; 95% CI, 1.05-2.75). The BBT and IBE groups had a significantly higher rate of type II endoleaks (17.63% and 16.95%, respectively; P = .03). The EIE group had a higher rate of type Ib endoleaks (1.9%) compared with the BBT (1.1%), IBE (1.7%), and control (0.3%) groups (P = .01). No differences were found between the groups in terms of postoperative myocardial infarction (P = .47) or respiratory (P = .61) or intestinal (P = .71) complications. However, the rates of limb complications and reoperation were higher in the EIE group.
The present study revealed that the EIE technique was more likely to demonstrate shrinkage in the aortic aneurysmal diameter than were the BBT and IBE groups compared with the control group on multivariable analysis. The EIE technique was also more likely to result in aneurysmal sac shrinkage than was the BBT group, albeit with greater rates of limb-related complications.
腹主动脉瘤(AAA)向髂总动脉(CIA)的动脉瘤延伸给成功的血管内腹主动脉瘤修复(EVAR)带来了技术挑战。在本研究中,我们比较了 Bell-bottom 技术(BBT)、髂内动脉栓塞和髂外动脉延伸(EIE)以及髂分支支架(IBE)后瘤囊收缩和围手术期结果。
利用血管质量倡议数据库,对 2013 年至 2019 年接受 EVAR 的患者进行了回顾性分析。分析了人口统计学、解剖学和围手术期数据。所有近端主动脉颈长度<10mm 和主动脉移植物直径>32mm 的患者均被排除在分析之外。根据远端肢体策略将患者分为四组:第 1 组为双侧髂总动脉肢体<20mm 的对照组;第 2 组为单侧或双侧肢体>20mm 的 BBT 组;第 3 组为 EIE 技术组;第 4 组为 IBE 组。主要终点是随访期间主动脉直径的最大变化。次要终点包括术后并发症和内漏率。
查询了 14455 例接受 EVAR 的患者的记录,其中 5788 例符合解剖标准。平均年龄为 73 岁,86.3%为男性。对照组、BBT 组、IBE 组和 EIE 组的主动脉直径最大变化分别为-7.2mm、-6.1mm、-4.6mm 和-6.8mm(P=.06)。在平均随访 405 天的单变量分析中,差异无统计学意义。然而,多变量分析(P=.01)显示,与对照组相比,BBT 组和 IBE 组发生动脉瘤缩小的可能性分别降低了 18.4%(比值比[OR],0.816;95%置信区间[CI],0.68-0.98)和 48.0%(OR,0.52;95%CI,0.33-0.82)。相比之下,EIE 组与对照组在缩小方面没有显著差异。各组的多变量分析还表明,与 BBT 组相比,EIE 组发生主动脉瘤直径缩小的可能性增加了 69.5%(OR,1.70;95%CI,1.05-2.75)。BBT 组和 IBE 组的 II 型内漏发生率明显较高(分别为 17.63%和 16.95%;P=.03)。EIE 组的 Ib 型内漏发生率(1.9%)高于 BBT 组(1.1%)、IBE 组(1.7%)和对照组(0.3%)(P=.01)。各组之间在心肌梗死(P=.47)、呼吸(P=.61)或肠道(P=.71)并发症方面无差异。然而,EIE 组的肢体并发症和再次手术率较高。
本研究表明,与对照组相比,多变量分析显示 EIE 技术比 BBT 和 IBE 技术更有可能导致主动脉瘤直径缩小。与 BBT 组相比,EIE 技术也更有可能导致动脉瘤囊缩小,但肢端相关并发症的发生率更高。