Department of Otolaryngology, Queen Elizabeth University Hospital, Glasgow, Scotland, UK.
Department of Otolaryngology, Ninewells Hospital, Dundee, Scotland, UK.
J Laryngol Otol. 2022 Oct;136(10):909-916. doi: 10.1017/S002221512100428X. Epub 2022 Jan 10.
This study aimed to assess the current literature on the safety and impact of in-office biopsy on cancer waiting times as well as review evidence regarding cost-efficacy and patient satisfaction.
A search of Cinahl, Cochrane Library, Embase, Medline, Prospero, PubMed and Web of Science was conducted for papers relevant to this study. Included articles were quality assessed and critically appraised.
Of 19 741 identified studies, 22 articles were included. Lower costs were consistently reported for in-office biopsy compared with operating room biopsy. Four complications requiring intervention were documented. In-office biopsy is highly tolerated, with a procedure abandonment rate of less than 1 per cent. When compared with operating room biopsy, it is associated with significantly reduced time-to-diagnosis and time-to-treatment initiation. It is linked to improved overall three-year survival.
In-office biopsy is a safe procedure that may help certain patients avoid general anaesthetic. It was shown to significantly reduce time-to-diagnosis and time-to-treatment initiation when compared with operating room biopsy. This may have important implications for oncological outcomes. In-office biopsy requires fewer resources and is likely to be cost-saving five-years following introduction. With high rates of sensitivity and specificity, in-office biopsy should be considered as the first-line procedure to achieve tissue diagnosis.
本研究旨在评估关于门诊活检的安全性和影响的现有文献，评估成本效益和患者满意度方面的证据。
对 Cinahl、Cochrane Library、Embase、Medline、Prospéro、PubMed 和 Web of Science 进行了检索，以获取与本研究相关的论文。纳入的文章进行了质量评估和批判性评价。
在 19741 项已确定的研究中，有 22 篇文章被纳入。与手术室活检相比，门诊活检的成本始终较低。有 4 例需要干预的并发症被记录。门诊活检具有较高的耐受性，其放弃率不到 1%。与手术室活检相比，它与诊断时间和治疗开始时间的显著缩短有关。它与整体三年生存率的提高有关。
门诊活检是一种安全的程序，可以帮助某些患者避免全身麻醉。与手术室活检相比，它显著缩短了诊断时间和治疗开始时间。这可能对肿瘤学结果有重要影响。门诊活检需要较少的资源，并且在引入后五年内可能具有成本效益。具有较高的敏感性和特异性，门诊活检应被视为获得组织诊断的一线程序。
