The Chemoradiotherapy Center, Ningbo No. 1 Hospital, Ningbo, Zhejiang 315000, China.
Contrast Media Mol Imaging. 2021 Dec 20;2021:9305508. doi: 10.1155/2021/9305508. eCollection 2021.
In order to study the application value of spiral CT lung density measurement software in the diagnosis of radioactive lung injury, the average CT values of lung apex, hilum, and diaphragm were measured by Pulmo automatic evaluation software of 16-slice spiral CT in 96 patients with different types of radiation lung injury diagnosed by conventional CT and 80 healthy subjects. The radiation lung injury on CT slices was classified, and the lung density was measured. In 96 patients with different types of radiation lung injury, 56 patients had different degrees of increase in average lung density, which was most obvious in the type of air insufficiency and chronic fibrosis. CT values of lung density in the ground glass stage and patch stage of acute radiation pneumonia had little influence due to the range and time of exposure. The lung density of 35 patients with radiation injury was measured in the normal range. There was a significant difference between normal lung density and abnormal lung density in different types of radiation lung injury ( = 56.718, < 0.001). The mean lung density of 68 cases was normal and that of 12 cases was abnormal. There was a significant difference in lung density between the lung injury group and the normal group ( = 18.027, < 0.001). Spiral CT lung density measurement can accurately evaluate the lung density values of different types of radiation lung injury and judge the correlation between lung density and different types of radiation lung injury. It is of great value to diagnose, locate, and master the radiation dose of different types of radiation lung injury.
为了研究螺旋 CT 肺密度测量软件在放射性肺损伤诊断中的应用价值，采用 16 层螺旋 CT 的 Pulmo 自动评价软件对常规 CT 诊断为不同类型放射性肺损伤的 96 例患者及 80 例健康对照者的肺尖、肺门及膈肌平均 CT 值进行测量，对 CT 片上放射性肺损伤进行分类，并测量肺密度。96 例不同类型放射性肺损伤患者中，56 例平均肺密度有不同程度增高，以气腔不全和慢性纤维化为最明显，急性放射性肺炎磨玻璃期和斑片期因曝光范围及时间不同，CT 值对肺密度影响较小。35 例放射性损伤患者的肺密度在正常范围内。不同类型放射性肺损伤正常肺密度与异常肺密度比较，差异有统计学意义（ = 56.718， < 0.001）。正常肺密度 68 例，异常肺密度 12 例。损伤组与正常组肺密度比较，差异有统计学意义（ = 18.027， < 0.001）。螺旋 CT 肺密度测量能准确评估不同类型放射性肺损伤的肺密度值，判断肺密度与不同类型放射性肺损伤的相关性，对诊断、定位及掌握不同类型放射性肺损伤的放射剂量有重要价值。
