van Giessen J W, Viergever M A, van Rijk P P, Gerritsen J G
Department of Mathematics and Informatics, Delft University of Technology, The Netherlands.
J Nucl Med. 1987 Dec;28(12):1892-900.
Two devices especially designed for tomographic thyroid imaging are compared on the basis of phantom experiments and four patients studies: a seven pinhole (7P) collimator and a time-coded aperture (TCA). The results of patient studies show that the 7P collimator may miss smaller abnormalities and is prone to incorrect positioning. The TCA reconstructions of patient data confirm the good performance observed in the phantom studies and demonstrate a high degree of lesion detectability. The TCA also provides higher efficiency and shorter imaging times than the 7P collimator. It is therefore concluded that TCA imaging is a promising alternative to multiple view pinhole imaging of the thyroid.
基于体模实验和对4例患者的研究，对两种专门设计用于甲状腺断层成像的设备进行了比较：一种是七针孔（7P）准直器，另一种是时间编码孔径（TCA）。对患者的研究结果表明，7P准直器可能会遗漏较小的异常，并且容易出现定位错误。患者数据的TCA重建证实了在体模研究中观察到的良好性能，并显示出高度的病变可检测性。与7P准直器相比，TCA还具有更高的效率和更短的成像时间。因此得出结论，TCA成像有望成为甲状腺多视角针孔成像的替代方法。
