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印度发育性髋关节发育不良(DDH)的发病率、诊断及治疗实践:一项范围界定性系统评价

The Incidence, Diagnosis, and Treatment practices of Developmental Dysplasia of Hip (DDH) in India: A Scoping Systematic Review.

作者信息

Chand Suresh, Aroojis Alaric, Pandey Ritesh A, Johari Ashok N

机构信息

Department of Paediatric Orthopaedics, King George's Medical University, Lucknow, Uttar Pradesh India.

Department of Paediatric Orthopaedics, Bai Jerbai Wadia Hospital for Children, Acharya Donde Marg, Parel, Mumbai, Maharashtra 400012 India.

出版信息

Indian J Orthop. 2021 Sep 24;55(6):1428-1439. doi: 10.1007/s43465-021-00526-y. eCollection 2021 Dec.

Abstract

PURPOSE

To identify literature on variations and knowledge gaps in the incidence, diagnosis, and management of developmental dysplasia of hip (DDH) in India.

METHODS

Following standard methodology and PRISMA-ScR guidelines, a scoping systematic review of literature on incidence, diagnosis, and treatment of DDH in India was conducted. Studies conducted in India, published in indexed or non-indexed journals between 1975 and March 2021, were included in the search.

RESULTS

Of 57 articles which met the inclusion criteria, only 33 studies (57.8%) were PubMed-indexed. Twenty-eight studies (49%) were published in Orthopaedic journals and majority had orthopaedic surgeon as the lead author (59.6%). Sixteen studies were mainly epidemiological, 20 reported screening/diagnosis, and 21 reported treatment of DDH. Almost 90% of the studies (51) were Level 4 or 5 according to the levels of evidence in research. There is lack of clarity in the definition of hip dysplasia and screening/diagnostic guidelines to be used. The incidence of hip dysplasia in India is reported to be 0-75 per 1000 live births, with true DDH between 0 and 2.6/1000. Late-presenting DDH is common in India, with most studies reporting a mean age of > 20 months for children presenting for treatment. The treatment is also varied and there is no clear evidence-based approach to various treatment options, with lack of long-term studies.

CONCLUSION

This systematic scoping review highlights various knowledge gaps pertaining to DDH diagnosis and management in India. High-quality, multicentric research in identified gap areas, with long-term follow-up, is desired in future.

摘要

目的

识别关于印度发育性髋关节发育不良(DDH)发病率、诊断及管理方面的差异和知识空白的文献。

方法

按照标准方法和PRISMA-ScR指南,对印度DDH发病率、诊断及治疗的文献进行范围界定的系统综述。纳入1975年至2021年3月间在印度开展、发表于索引或非索引期刊的研究。

结果

在符合纳入标准的57篇文章中,仅有33项研究(57.8%)被PubMed索引。28项研究(49%)发表于骨科期刊,且大多数研究的第一作者为骨科医生(59.6%)。16项研究主要为流行病学研究,20项报告了筛查/诊断情况,21项报告了DDH的治疗情况。根据研究证据水平,几乎90%的研究(51项)为4级或5级。髋关节发育不良的定义以及所使用的筛查/诊断指南尚不明确。据报道,印度髋关节发育不良的发病率为每1000例活产0至75例,真正的DDH为每1000例0至2.6例。晚发性DDH在印度很常见,大多数研究报告接受治疗的儿童平均年龄>20个月。治疗方法也各不相同,对于各种治疗选择缺乏明确的循证方法,且缺乏长期研究。

结论

本系统范围界定综述突出了印度在DDH诊断和管理方面的各种知识空白。未来需要在已确定的空白领域开展高质量、多中心且有长期随访的研究。

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本文引用的文献

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Screening of Newborns and Infants for Developmental Dysplasia of the Hip: A Systematic Review.
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Developmental Dysplasia of the Hip: An Examination of Care Practices of Orthopaedic Surgeons in India.
Indian J Orthop. 2020 Aug 20;55(1):158-168. doi: 10.1007/s43465-020-00233-0. eCollection 2021 Feb.
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