Monti C, Sabbatani S
Servizio di Radiologia, Ospedale Maggiore C. A. Pizzardi, Bologna.
Radiol Med. 1987 Nov;74(5):376-83.
After revising literature concerning Pneumocystis Carinii Pneumoniae (PCP), the authors undertook a close examination of the immunological system of the HIVab-positive patients that suffered opportunistic pneumopathy from PCP. Hundred-forty-three cases of HIVab-positive (mean age of 29), prevalently heroin drug-users, were studied. There were 13 AIDS, 26 ARC, 91 LAS cases and 13 patients with only Ab positivity for HIV. Four hundred chest radiographs were examined without previous knowledge of case histories. A small number of hilum and/or mediastinal lymphadenopathies was observed. Moreover, percentage increase in acute lung inflammatory diseases, mainly interstitial, was seen. These data were correlated to the worsening of the HIV infection and to the developing of LAS, ARC and AIDS. In a number of cases there was radiological evidence of progressed inflammatory episodes. The clinical pattern of PCP patients is dramatic and often fatal. Clinical-radiological cases with special reference to acute interstitial disease, caused by opportunistic agents, are presented.
在查阅有关卡氏肺孢子虫肺炎(PCP)的文献后,作者对患有PCP机会性肺病的HIV抗体阳性患者的免疫系统进行了仔细检查。研究了143例HIV抗体阳性患者(平均年龄29岁),他们主要是海洛因吸毒者。其中有13例艾滋病患者、26例艾滋病相关综合征(ARC)患者、91例艾滋病相关症状(LAS)患者以及13例仅HIV抗体呈阳性的患者。在不了解病史的情况下检查了400张胸部X光片。观察到少数肺门和/或纵隔淋巴结病。此外,还发现主要为间质性的急性肺部炎症性疾病有所增加。这些数据与HIV感染的恶化以及LAS、ARC和艾滋病的发展相关。在一些病例中,有炎症发作进展的放射学证据。PCP患者的临床症状严重,往往致命。本文介绍了特别涉及由机会性病原体引起的急性间质性疾病的临床放射学病例。