Aĭtpaev B K, Seĭsembekov T Z
Ter Arkh. 1987;59(8):59-63.
Chronic pyelonephritis at the stage of exacerbation is accompanied by the development of combined immunodeficiency characterized by the inhibition of some humoral factors of nonspecific resistance, a decrease in the functional potential of the system of neutrophilic phagocytosis, quantitative deficiency of the circulating pool of thymus-dependent lymphocytes and a decrease in their functional activity combined with disturbance of antibody genesis. Immunomodulating therapy against a background of multiple modality therapy of disease was proposed.
慢性肾盂肾炎急性发作期伴有联合免疫缺陷的发展，其特征为非特异性抵抗的一些体液因子受到抑制、嗜中性粒细胞吞噬系统的功能潜力降低、胸腺依赖性淋巴细胞循环池数量不足及其功能活性下降，同时伴有抗体生成紊乱。有人提出在疾病的多模式治疗背景下进行免疫调节治疗。
