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[西柏林地区地方性口炎性腹泻的发病率。一项基于活检结果的回顾性研究]

[Incidence of endemic sprue in Berlin (West). A retrospective study based on biopsy findings].

作者信息

Gutschmidt S, Sandforth F, Janicke I, Lüders C J, Niedobitek F, Stein H, Stolpmann H J, Vogel M, Riecken E O

机构信息

Fachklinik Fränkische Saale, Bad Neustadt/Saale.

出版信息

Z Gastroenterol. 1987 Oct;25(10):662-7.

PMID:3500554
Abstract

The incidence of celiac disease in Berlin (West) during the years 1979-1984 has been studied retrospectively by investigating the records of the local Pathological Institutes, which examine small intestinal biopsies, for the occurrence of abnormal specimens typical of celiac disease (group 1) or consistent with the diagnosis of celiac disease (group 2). Group 1 exhibited a constant average incidence of 0.74 per 100,000 inhabitants per year, while group 2 showed a small increase between 1979 and 1984, averaging 1.03 per 100,000 inhabitants per year. Classified according to age the highest incidence was seen in the 0-5 year-olds, namely 8.04 in group 1 and 10.00 in group 2. For those children born and examined during the period of investigation the values ranged between 15.8 and 64.7 per 100,000 births. Girls, with an average frequency of 1:1919 births were more often affected than boys, who averaged 1:4219 births. These figures obtained in Berlin (West) indicate only the lower ranges of incidences and will have to be further supplemented by a prospective study.

摘要

通过调查当地病理研究所的记录,对1979 - 1984年间西柏林乳糜泻的发病率进行了回顾性研究。这些研究所负责检查小肠活检样本,以确定是否存在乳糜泻典型的异常样本(第1组)或符合乳糜泻诊断的样本(第2组)。第1组的年平均发病率为每10万居民0.74例,而第2组在1979年至1984年间略有上升,年平均发病率为每10万居民1.03例。按年龄分类,发病率最高的是0 - 5岁儿童,第1组为8.04例,第2组为10.00例。对于在调查期间出生并接受检查的儿童,每10万例出生中的发病率在15.8至64.7例之间。女孩受影响的频率平均为1:1919出生,高于男孩,男孩的平均频率为1:4219出生。在西柏林获得的这些数据仅表明发病率的较低范围,还需要通过前瞻性研究进一步补充。

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