Department of Pediatric Infectious Diseases, UH Cleveland Medical Center - Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Avera McKennan Children's Hospital and University Health Center, Sioux Falls, South Dakota.
S D Med. 2021 Nov;74(11):519-522.
Community-acquired Acinteobacter baumanii (AB) infection in the pediatric population is a rare entity in developed countries. Most of the cases in literature have been reported from India and Pakistan. Few cases of pediatric AB infection have been reported in the U.S., the vast majority of which have been from the neonatal intensive care unit population. The ubiquitous nature of the organism makes it challenging to isolate and identify as a true pathogen. For this same reason, it is imperative to have a high degree of suspicion for AB infection especially in infants and immunocompromised patients particularly when no other etiologic agent is isolated. We present a case of a healthy 37-day-old full-term neonate who presented with sepsis from Acinetobacter baumanii identified by matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry. The patient responded well to timely administration of antibiotics. She received 14-day course of cefepime based on culture susceptibility with no reported complications.
在发达国家,儿童获得性鲍曼不动杆菌(AB)感染是一种罕见的疾病。文献中的大多数病例均来自印度和巴基斯坦。美国也有少数几例儿科 AB 感染病例,其中绝大多数来自新生儿重症监护病房。该菌无处不在,难以分离和鉴定为真正的病原体。出于同样的原因,对于 AB 感染,特别是在没有其他病原体分离的情况下,对于婴儿和免疫功能低下的患者,必须高度怀疑。我们报告了一例 37 天大的足月新生儿,该患儿因鲍曼不动杆菌引起的败血症就诊,通过基质辅助激光解吸/电离飞行时间(MALDI-TOF)质谱法鉴定。该患者对及时给予抗生素治疗反应良好。根据药敏试验,她接受了 14 天头孢吡肟治疗,无报道的并发症。