Dabos N, Levasseur A L, Bertrand M, Guery J, Lecestre P, Benoit J, Ramadier J O
Anesth Analg (Paris). 1977 Sep-Oct;34(5):951-61.
Aseptic osteonecrosis following renal transplantation occurs in about 20 p. 100 of cases and entails important functional consequences. 16 patients with kidney transplant and 4 patients on chronic dialysis because of previous graft rejection underwent 27 orthopaedic operations, 8 of which being hip arthroplasties. During and after the procedure the anesthesiologist had to manage with drug interaction, coagulation disorders, blood compatibility problems etc... Despite poor general condition of patients and the risk of infectious complications linked to the never interrupted immunosupressive treatment, the surgical results of our serial were good.
肾移植后无菌性骨坏死发生率约为2%，会导致严重的功能后果。16例肾移植患者和4例因既往移植排斥反应而接受慢性透析的患者接受了27次骨科手术，其中8例为髋关节置换术。在手术过程中和术后，麻醉医生必须应对药物相互作用、凝血障碍、血液相容性问题等。尽管患者总体状况不佳，且因持续进行免疫抑制治疗存在感染并发症风险，但我们这一系列手术的结果良好。
