[肝脏单光子发射计算机断层扫描临床疗效的协作组研究]

[A cooperative group study of clinical efficacy of the liver SPECT].

作者信息

Mori Y, Kawakami K, Machida K, Oyamada H, Matsumoto T, Iinuma T, Makita K, Okada Y, Kosaka N, Nishikawa J

机构信息

Jikei University School of Medicine, Tokyo, Japan.

出版信息

Radioisotopes. 1987 Sep;36(9):457-64. doi: 10.3769/radioisotopes.36.9_457.

DOI:10.3769/radioisotopes.36.9_457

PMID:3501136

Abstract

The purpose of this study is to evaluate the clinical efficacy of the liver SPECT about detectability of SOLs (space occupying lesion). The images were interpreted with the planar scintigram (PS) only and combination of PS and SPECT (single photon emission computed tomography) by 11 physicians. Changes of false positive and false negative rate were calculated to evaluate the influence of the diffuse parenchymal liver disease and the localization of the SOLs. Addition of SPECT to PS in the cases who are suspected SOLs is effective in right hepatic lobe (right anterior and posterior segment) to detect the SOLs, but not effective in left lateral segment. Addition of SPECT to PS in the cases with diffuse parenchymal liver disease and SOLs increases the false positive rate.

摘要

本研究的目的是评估肝脏SPECT对检测肝内占位性病变（SOLs）的临床疗效。11名医生仅通过平面闪烁图（PS）以及PS与单光子发射计算机断层扫描（SPECT）相结合的方式对图像进行解读。计算假阳性率和假阴性率的变化，以评估弥漫性肝实质疾病和SOLs定位的影响。对于疑似SOLs的病例，在PS基础上加用SPECT对检测右肝叶（右前和后段）的SOLs有效，但对左外叶无效。对于患有弥漫性肝实质疾病和SOLs的病例，在PS基础上加用SPECT会增加假阳性率。