Baroni Adone, Verolino Pasquale
Department of Dermatology and Venereology, University of Campania "Luigi Vanvitelli", 80131 Napoli, Italy.
Plastic Surgery Unit, University of Campania "Luigi Vanvitelli", 80120 Napoli, Italy.
J Clin Med. 2021 Dec 27;11(1):140. doi: 10.3390/jcm11010140.
Scars are a common disfiguring sequela of various events such as acne, hidradenitis suppurativa, surgery, trauma, and burns, which can lead to serious psychosocial problems with a negative effect on the quality of life. Many conventional approaches have been proposed for the treatment of scars, including surgical techniques, dermabrasion, chemical peels, topical silicone gel, 5-fluorouracile and dermal fillers injection or autologous fat transfer for atrophic scars, and corticosteroids injection for hypertrophic and keloid scars; however, they have sporadic effects. Ablative lasers, such as carbon dioxide laser or Erbium Yag laser, are associated with many collateral effects limiting their application. Non-ablative laser treatments have been shown to be safer and to have fewer side effects, but they have a reduction of clinical efficacy compared to ablative lasers and a minimal improvement of scars. The demand for minimal invasive and safe technology for the treatment of a scars has stimulated the search for more effective novel therapy with fewer collateral effects. Plasma radiofrequency ablation is a new technique consisting of the generation of plasma energy through the production of ionized energy, which thermally heats tissue in a uniform and controlled manner, through a plasma radiofrequency device, inducing a sublimation of the tissue. The aim of this study is to evaluate the effectiveness of P-RF ablation in the treatment of scars performed with D.A.S. Medical device (Technolux, Italia), which is a tool working with the long-wave plasma radiofrequency principle.
疤痕是痤疮、化脓性汗腺炎、手术、创伤和烧伤等各种情况常见的毁容性后遗症，会导致严重的心理社会问题，对生活质量产生负面影响。针对疤痕的治疗已提出许多传统方法，包括手术技术、磨皮术、化学换肤、外用硅胶凝胶、5-氟尿嘧啶以及针对萎缩性疤痕的真皮填充剂注射或自体脂肪移植，还有针对增生性和瘢痕疙瘩性疤痕的皮质类固醇注射；然而，这些方法效果不一。剥脱性激光，如二氧化碳激光或铒钇铝石榴石激光，存在许多附带影响，限制了它们的应用。非剥脱性激光治疗已被证明更安全且副作用更少，但与剥脱性激光相比，其临床疗效有所降低，对疤痕的改善也微乎其微。对治疗疤痕的微创且安全技术的需求促使人们寻找副作用更少的更有效新疗法。等离子射频消融是一种新技术，通过产生电离能量来产生等离子体能量，通过等离子射频设备以均匀且可控的方式对组织进行热加热，从而使组织升华。本研究的目的是评估使用D.A.S.医疗器械（Technolux，意大利）进行的等离子射频消融治疗疤痕的有效性，该器械是一种基于长波等离子射频原理工作的工具。
