Zhu W, Shan S S, Zhang Q Y, Zhang J, Zhang C Y, Wang C Y, Jia Z M, Zhang G X, Wang Y, Che Y Y, Wen J G, Wang Q W
Department of Urology, the First Affiliated Hospital of Zhengzhou University, Henan 450000, China.
Henan Joint International Pediatric Urodynamic Laboratory, the First Affiliated Hospital of Zhengzhou University, Henan 450000, China.
Zhonghua Yi Xue Za Zhi. 2022 Jan 11;102(2):147-151. doi: 10.3760/cma.j.cn112137-20210408-00849.
A total of 16 detrusor hyperactivity with impaired contractility (DHIC) patients who received 12 weeks remote variable frequency stimulation (VFS) were enrolled at the First Affiliated Hospital of Zhengzhou University from September 2020 to February 2021. The voiding diary, symptom score scales and incidence of complications were completed and recorded at baseline, constant frequency stimulation (CFS) and VFS phases. Compared with the CFS phase, voiding times, urge incontinence times and daily catheterization volume were reduced; average voiding amount and functional bladder capacity increased; and the quality of life score and mental health questionnaire assessment were improved in the VFS phase(all <0.05). In the end, among all 16 patients, there were 14 whose symptoms had improved, and there were no new complications such as pain or infection at the implantation site, electrode displacement, and electric shock sensation in the stimulation area. VFS-SNM can not only improve the DHIC patients' lower urinary tract symptoms during storage and urination period, but also improve the patients' quality of life and satisfaction of the therapy.
2020年9月至2021年2月，郑州大学第一附属医院共纳入16例接受12周远程可变频率刺激（VFS）的逼尿肌过度活动伴收缩功能受损（DHIC）患者。在基线、恒频刺激（CFS）和VFS阶段完成并记录排尿日记、症状评分量表及并发症发生率。与CFS阶段相比，VFS阶段排尿次数、急迫性尿失禁次数及每日导尿量减少；平均排尿量和功能性膀胱容量增加；生活质量评分及心理健康问卷评估得到改善（均P<0.05）。最终，16例患者中14例症状改善，且未出现植入部位疼痛或感染、电极移位、刺激区域电击感等新的并发症。VFS-SNM不仅能改善DHIC患者储尿期和排尿期的下尿路症状，还能提高患者生活质量及治疗满意度。
