Protecting blinded trials in electronic hospital systems.
作者信息
Sydes Matthew R, Wong Wai Keong, Bakhai Ameet, Joffe Nicola, Love Sharon B
机构信息
Institute of Clinical Trials and Methodology, MRC Clinical Trials Unit at UCL, London, UK.
British Heart Foundation Data Science Centre, London, UK.
出版信息
Clin Trials. 2022 Apr;19(2):231-233. doi: 10.1177/17407745211069985. Epub 2022 Jan 11.
Abstract
摘要
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Protecting blinded trials in electronic hospital systems.在电子医院系统中保护盲法试验。
Clin Trials. 2022 Apr;19(2):231-233. doi: 10.1177/17407745211069985. Epub 2022 Jan 11.
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本文引用的文献
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Blindsided: challenging the dogma of masking in clinical trials.措手不及：挑战临床试验中设盲的教条。
BMJ. 2020 Jan 21;368:m229. doi: 10.1136/bmj.m229.
2
Impact of blinding on estimated treatment effects in randomised clinical trials: meta-epidemiological study.随机临床试验中盲法对估计治疗效果的影响：meta 流行病学研究。
BMJ. 2020 Jan 21;368:l6802. doi: 10.1136/bmj.l6802.
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Fool's gold? Why blinded trials are not always best.愚人金？为何盲法试验并非总是最佳选择。
BMJ. 2020 Jan 21;368:l6228. doi: 10.1136/bmj.l6228.
4
Unreported formal assessment of unblinding occurred in 4 of 10 randomized clinical trials, unreported loss of blinding in 1 of 10 trials.在10项随机临床试验中，有4项未报告破盲的正式评估情况，10项试验中有1项未报告盲法的丧失情况。
J Clin Epidemiol. 2017 Jan;81:42-50. doi: 10.1016/j.jclinepi.2016.08.002. Epub 2016 Aug 20.
5
The importance of allocation concealment and patient blinding in osteoarthritis trials: a meta-epidemiologic study.骨关节炎试验中分配隐藏和患者盲法的重要性：一项元流行病学研究。
Arthritis Rheum. 2009 Dec 15;61(12):1633-41. doi: 10.1002/art.24894.
6
Who is blinded in randomized clinical trials? A study of 200 trials and a survey of authors.在随机临床试验中谁被设盲了？对200项试验的研究及对作者的调查。
Clin Trials. 2006;3(4):360-5. doi: 10.1177/1740774506069153.
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