Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
BMC Res Notes. 2022 Jan 10;15(1):13. doi: 10.1186/s13104-021-05899-9.
Musculoskeletal pain conditions (MPs) are a widespread public problem that can affect 13.5% to 47% of the total population. Dietary changes can have strong effects on person's health; for instance, Sulfur amino acids (SAAs) can act as a precursor of neurotransmitters, antioxidative metabolic intermediates, such as glutathione, impact inflammation, and play a role in severity and frequency of MPs. We evaluated the relationship between dietary SAAs intake with severity and frequency of pain in patients with MPs.
This cross-sectional study consisted of 175 men and woman. Anthropometric measurements and pain assessments were conducted via questionnaires. Dietary data were collected using 7 days 24-h recall. ANOVA and Spearman correlation coefficients were used to examine the relationship and correlation, respectively, between exposure and outcome variables. There was a significant correlation between age, weight, waist circumference (WC), waist circumference to height (WHtR), body mass index (BMI), and severity and frequency of MPs among women. There was a correlation between age and severity of pain in men. The present study highlights a positive association between the dietary SAAs and severity of pain, even after adjusting for confounding variables.
肌肉骨骼疼痛疾病（MPs）是一个广泛存在的公共问题，可影响总人口的 13.5%至 47%。饮食的改变对人的健康有很大的影响；例如，含硫氨基酸（SAAs）可以作为神经递质、抗氧化代谢中间体（如谷胱甘肽）的前体，影响炎症，并在 MPs 的严重程度和频率中发挥作用。我们评估了饮食中 SAAs 的摄入量与 MPs 患者疼痛严重程度和频率之间的关系。
这项横断面研究包括 175 名男性和女性。通过问卷进行了人体测量和疼痛评估。使用 7 天 24 小时回顾法收集饮食数据。使用方差分析（ANOVA）和斯皮尔曼相关系数分别检验暴露和结局变量之间的关系和相关性。女性的年龄、体重、腰围（WC）、腰围身高比（WHtR）、体重指数（BMI）和 MPs 的严重程度和频率之间存在显著相关性。男性的年龄与疼痛严重程度之间存在相关性。本研究强调了饮食中 SAAs 与疼痛严重程度之间的正相关关系，即使在调整了混杂变量后也是如此。
