Suppr超能文献

腭裂修复术中类固醇的应用:单外科医生比较回顾性队列研究。

Steroid Use in Palatoplasty: A Single Surgeon Comparative Retrospective Cohort Study.

机构信息

Department of Plastic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

出版信息

J Craniofac Surg. 2022;33(2):526-529. doi: 10.1097/SCS.0000000000008305.

Abstract

BACKGROUND

Fistula rates in cleft palate repair vary by technique, surgeon, and institution. Although steroids are commonly used in airway surgery, many plastic surgeons are reluctant to use steroids because of concerns with wound healing. This study aims to assess outcomes and safety of steroid use in Furlow palatoplasty and determine its impact on fistula formation.

METHODS

A retrospective cohort study was done of all cleft palate surgeries performed by a single surgeon between 2010 and 2014. Data reviewed included demographics, type of cleft, steroid use, length of surgery, length of stay, and fistula formation rate.

RESULTS

One hundred thirty-five patients underwent palatoplasty, of which 101 received steroids and 34 did not. The mean age was 4.6 years. A total of 42.2% of patients underwent primary palatoplasty, 48.1% underwent submucous cleft palatoplasty, and 9.7% underwent conversion palatoplasty. The overall fistula rate was 1.5% and was comparable between the 2 groups (steroids = 2.0%, no steroids = 0.0%, P = 0.558), and all occurred in primary palatoplasty patients. The average length of stay in the hospital was shorter among patients receiving steroids (steroids = 2.0 days, no steroids = 2.5 days, P < 0.05).

CONCLUSIONS

Steroid use in cleft palate surgery appears to be safe and likely not associated with impaired wound healing or increased fistula formation. It may also shorten length of hospitalization.

摘要

背景

腭裂修复术的瘘管发生率因技术、外科医生和机构而异。尽管类固醇在气道手术中被广泛应用,但许多整形外科医生因担心伤口愈合而不愿意使用类固醇。本研究旨在评估类固醇在 Furlow 腭裂修复术中的使用效果和安全性,并确定其对瘘管形成的影响。

方法

对 2010 年至 2014 年间由一位外科医生进行的所有腭裂手术进行了回顾性队列研究。回顾的数据包括人口统计学资料、腭裂类型、类固醇使用情况、手术时间、住院时间和瘘管形成率。

结果

共有 135 例患者接受了腭裂修复术,其中 101 例接受了类固醇治疗,34 例未接受。平均年龄为 4.6 岁。共有 42.2%的患者接受了初次腭裂修复术,48.1%的患者接受了黏膜下腭裂修复术,9.7%的患者接受了转换腭裂修复术。总的瘘管发生率为 1.5%,两组之间无差异(类固醇组为 2.0%,无类固醇组为 0.0%,P=0.558),所有瘘管均发生在初次腭裂修复术患者中。接受类固醇治疗的患者住院时间较短(类固醇组为 2.0 天,无类固醇组为 2.5 天,P<0.05)。

结论

类固醇在腭裂手术中的使用似乎是安全的,不太可能与伤口愈合不良或瘘管形成增加有关。它还可能缩短住院时间。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验