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COVID-19 感染及其在肿瘤外科患者中的后果:系统分析、荟萃分析和荟萃回归。

COVID-19 infection and its consequences among surgical oncology patients: A systematic analysis, meta-analysis and meta-regression.

机构信息

Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Department of Cardiac Surgery, Spedali Civili di Brescia, Brescia, Italy.

出版信息

J Surg Oncol. 2022 Apr;125(5):813-823. doi: 10.1002/jso.26787. Epub 2022 Jan 11.

Abstract

We conducted this meta-analysis to address the outcomes in cancer patients after oncologic surgery during COVID-19 pandemic. The primary endpoint was the COVID-19-related mortality rate. Higher body mass index was significantly and negatively associated with higher all-cause mortality and in-hospital COVID-19 infection rates. Male sex, preoperative respiratory disease, and smoking history were positively and significantly associated with increased all-cause mortality rates. Furthermore, male sex was positively and significantly associated with the COVID-19 infection rate.

摘要

我们进行了这项荟萃分析,以探讨在 COVID-19 大流行期间接受肿瘤手术后癌症患者的结局。主要终点是 COVID-19 相关死亡率。较高的体重指数与较高的全因死亡率和住院 COVID-19 感染率呈显著负相关。男性、术前呼吸系统疾病和吸烟史与全因死亡率的增加呈显著正相关。此外,男性与 COVID-19 感染率呈显著正相关。

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