Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, Karnataka, India.
Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, Karnataka, India.
Asian J Psychiatr. 2022 Mar;69:103004. doi: 10.1016/j.ajp.2022.103004. Epub 2022 Jan 4.
Catatonia has been reported as one among many neuropsychiatric manifestations associated with COVID-19 infection. Catatonia and COVID-19 co-occurrence remain clinical concerns, often posing challenges pertaining to diagnosis, and especially management. Limited information is available regarding the appropriate approaches to the management of catatonia in COVID-19 infection, particularly with reference to the safety and efficacy of benzodiazepines and Electro-convulsive therapy (ECT). We present our experience of five patients with catatonia consequent to heterogeneous underlying causes and concurrent COVID-19 infection, who received care at the psychiatric COVID unit of our tertiary care psychiatric hospital. An interesting observation included varying underlying causes for catatonia and the potential role that COVID-19 infection may have played in the manifestation of catatonia. In our experience, new-onset catatonia with or without pre-existing psychiatric illness and concurrent COVID-19 can be safely and effectively managed with lorazepam and/or ECTs. However, critical to the same is the need to implement modified protocols that integrate pre-emptive evaluation for COVID-19 disease and proactive monitoring of its relevant clinical parameters, thereby permitting judicious and timely implementation of catatonia-specific treatment options.
据报道,紧张症是 COVID-19 感染相关的许多神经精神表现之一。紧张症和 COVID-19 的同时发生仍然是临床关注的问题,这常常给诊断带来挑战,尤其是在管理方面。关于 COVID-19 感染时紧张症的适当管理方法,特别是关于苯二氮䓬类药物和电休克疗法(ECT)的安全性和疗效,目前信息有限。我们介绍了在我们的三级精神病医院的精神病 COVID 病房接受治疗的 5 例因异质潜在原因和并发 COVID-19 感染而导致紧张症的患者的经验。一个有趣的观察结果包括紧张症的不同潜在原因以及 COVID-19 感染可能在紧张症表现中起的潜在作用。根据我们的经验,新发的伴有或不伴有先前存在的精神疾病的紧张症以及并发 COVID-19 可以通过劳拉西泮和/或 ECT 安全有效地治疗。然而,同样重要的是需要实施修改后的方案,包括对 COVID-19 疾病进行预防性评估和积极监测其相关临床参数,从而可以明智地及时实施针对紧张症的治疗选择。