[Regulation of the heat resistance of muscle fibers in Rana temporaria tadpoles by selecting the parental gametes using quaternary ammonium compounds and chelators].

In experiments on the frog Rana temporaria, studies have been made on the effect of selection of the parental sperm by quaternary ammonium compounds--tetraethylammonium and tetramethylammonium, as well as by chelating agents--EDTA and EGTA--on the heat resistance of muscle tissue in the progeny of the first generation. It was found that selection of the sperm for its maximum stability to the injurious (immobilizing) effect of these drugs affects quantitative relationship in the family between tadpoles with a high and low heat resistance of muscle fibers. Insemination of the eggs by the sperm with maximum stability to elimination by TEA and TMA favours the development of tadpoles with relatively low heat resistance of muscle fibers. On the contrary, sperm selection by EDTA and EDTA increases the amount of tadpoles with a higher heat resistance of muscles.