微波消融治疗早期肝泡型包虫病的疗效分析：一项基于倾向评分匹配的研究
Analysis of the efficacy of microwave ablation in the treatment of early hepatic alveolar echinococcosis: A propensity score matching based study.
作者信息
Deng Xu, Wang Jing-Jing, Huang Han-Sheng, Zhang Ling-Qiang, Wang Zhi-Xin, Wang Kai-Qiang, Yang Xiao-Zhou, He Shao-Shuai, Li Zhao, Gao Ying, Wang Hai-Jiu, Fan Hai-Ning, Cairang Yangdan
机构信息
Department of Hepatopancreatobiliary Surgery, the Affiliated Hospital of Qinghai University, Xining, China; The Research Key Laboratory for Echinococcosis of Qinghai Province, Xining, China.
Department of Hepatopancreatobiliary Surgery, the Affiliated Hospital of Qinghai University, Xining, China; The Research Key Laboratory for Echinococcosis of Qinghai Province, Xining, China.
出版信息
Acta Trop. 2022 Apr;228:106307. doi: 10.1016/j.actatropica.2022.106307. Epub 2022 Jan 10.
BACKGROUND
To explore the efficacy of microwave ablation (MWA) in the treatment of hepatic alveolar echinococcosis (HAE) with a diameter of ≤5 cm.
METHOD
From June 2014 to January 2020, patients diagnosed with HAE were retrospectively analyzed. After balancing the confounding factors by propensity score matching (PSM) , the patients were divided into MWA group (n = 20) and radical operation group (n = 20) by 1:1 matching. The safety and effectiveness of MWA were assessed by comparing the differences between the two groups in terms of postoperative general laboratory indices, grading of postoperative complications, length of postoperative hospitalization, the outcome of treatment, and disease recurrence.
RESULT
After PSM, all confounders were not statistically different (P>0.05) . Compared with the radical surgery group, patients in the MWA group had lower postoperative ALT and WBC elevations (P<0.001) , shorter postoperative hospital stay (P<0.001) ) , lower hospital costs (P<0.001) . The effective rate of the two groups was 100%. There was no statistical difference in the incidence of postoperative complications and recurrence rate (P>0.05).
CONCLUSION
MWA is a safe and effective means of treating HAE ≤ 5 cm in diameter.
背景
探讨微波消融（MWA）治疗直径≤5 cm的肝泡型包虫病（HAE）的疗效。
方法
回顾性分析2014年6月至2020年1月诊断为HAE的患者。通过倾向得分匹配（PSM）平衡混杂因素后，将患者按1:1匹配分为MWA组（n = 20）和根治性手术组（n = 20）。通过比较两组术后一般实验室指标、术后并发症分级、术后住院时间、治疗效果和疾病复发情况的差异，评估MWA的安全性和有效性。
结果
PSM后，所有混杂因素无统计学差异（P>0.05）。与根治性手术组相比，MWA组患者术后ALT和WBC升高幅度更低（P<0.001），术后住院时间更短（P<0.001），住院费用更低（P<0.001）。两组有效率均为100%。术后并发症发生率和复发率无统计学差异（P>0.05）。
结论
MWA是治疗直径≤5 cm的HAE的一种安全有效的方法。
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