University of Ottawa, Ottawa, Ontario, Canada
University of Ottawa, Ottawa, Ontario, Canada.
BMJ Open. 2022 Jan 11;12(1):e053375. doi: 10.1136/bmjopen-2021-053375.
High mortality rates, anxiety and distress associated with Ebola virus disease (EVD) are risk factors for mood disorders in affected communities. This study aims to document the prevalence and risk factors associated with depressive symptoms among a representative sample of individuals affected by EVD.
Cross-sectional study.
The current study was conducted 7 months (March 11, 2019 to April 23, 2019) after the end of the ninth outbreak of EVD in the province of Equateur in the Democratic Republic of the Congo (DRC).
A large population-based sample of 1614 adults (50% women, M=34.05; SD=12.55) in health zones affected by the ninth outbreak in DRC.
Participants completed questionnaires assessing EVD exposure level, stigmatisation related to EVD and depressive symptoms. The ORs associated with sociodemographic data, EVD exposure level and stigmatisation were analysed through logistic regressions.
Overall, 62.03% (95% CI 59.66% to 64.40%) of individuals living in areas affected by EVD were categorised as having severe depressive symptoms. The multivariable logistic regression analyses showed that adults in the two higher score categories of exposure to EVD were at two times higher risk of developing severe depressive symptoms (respectively, OR 1.94 (95% CI 1.22 to 3.09); OR 2.34 (95% CI 1.26 to 4.34)). Individuals in the two higher categories of stigmatisation were two to four times more at risk (respectively, OR 2.42 (95% CI 1.53 to 3.83); OR 4.73 (95% CI 2.34 to 9.56)). Living in rural areas (OR 0.19 (95% CI 0.09 to 0.38)) and being unemployed (OR 0.68 (95% CI 0.50 to 0.93)) increased the likelihood of having severe depressive symptoms.
Results indicate that depressive symptoms in EVD affected populations is a major public health problem that must be addressed through culturally adapted mental health programs.
埃博拉病毒病（EVD）相关的高死亡率、焦虑和痛苦是受影响社区内情绪障碍的风险因素。本研究旨在记录在埃博拉病毒病影响人群中，代表性样本中与抑郁症状相关的患病率和风险因素。
横断面研究。
本研究于刚果民主共和国赤道省第九次埃博拉疫情结束后 7 个月（2019 年 3 月 11 日至 2019 年 4 月 23 日）进行。
刚果民主共和国赤道省第九次埃博拉疫情影响地区的一个由 1614 名成年人组成的大型基于人群的样本（50%为女性，M=34.05；SD=12.55）。
参与者完成了评估埃博拉病毒病暴露水平、与埃博拉病毒病相关的污名化和抑郁症状的问卷。通过逻辑回归分析了与社会人口统计学数据、埃博拉病毒病暴露水平和污名化相关的 OR。
总体而言，生活在埃博拉病毒病影响地区的个体中有 62.03%（95%置信区间为 59.66%至 64.40%）被归类为患有严重抑郁症状。多变量逻辑回归分析表明，埃博拉病毒病暴露水平较高的两个评分类别中的成年人患严重抑郁症状的风险增加两倍（分别为，OR 1.94（95%CI 1.22 至 3.09）；OR 2.34（95%CI 1.26 至 4.34））。处于两个较高污名化类别的个体的风险增加两到四倍（分别为，OR 2.42（95%CI 1.53 至 3.83）；OR 4.73（95%CI 2.34 至 9.56））。居住在农村地区（OR 0.19（95%CI 0.09 至 0.38））和失业（OR 0.68（95%CI 0.50 至 0.93））增加了严重抑郁症状的可能性。
结果表明，埃博拉病毒病影响人群中的抑郁症状是一个重大的公共卫生问题，必须通过文化适应的心理健康计划来解决。
