Division of Nephrology, Department of Internal Medicine, Federal Medical Centre, Bida, Niger State, Nigeria.
Division of Nephrology, Department of Internal Medicine, University of Benin Teaching Hospital, Benin, Edo State, Nigeria.
Saudi J Kidney Dis Transpl. 2021 Mar-Apr;32(2):445-454. doi: 10.4103/1319-2442.335457.
In Nigeria, there is paucity of data on malnutrition among chronic kidney disease (CKD) patients especially before the initiation of dialysis therapy, necessitating this study. The study subjects consisted of 96 CKD patients recruited from the renal unit of our hospital. Forty age-and sex-matched controls were also studied. Nutritional status was assessed using Subjective Global Assessment (SGA), weight change over six months of follow-up, body mass index, mid-upper arm circumference, triceps skinfold thickness, and serum albumin concentration. A three-day food diary was used to determine the average daily protein intake of the patients. Sixty-six CKD patients completed the study. The age range of CKD patients was 23-65 years with a mean of 47.1 ± 13.2 years while the age range of the controls was 23-65 years with a mean of 44.1 ± 14.3 years. Out of the 66 CKD patients studied, four lost >10% of their body weight. The body mass index (BMI) was low (<20 kg/m) in eight (12.1%) of CKD patients, while three (7.5%) subjects in the control population had BMI of <20 kg/m. The serum albumin was less than 3 g/dL in seven (10.6%) of the CKD patients, SGA identified malnutrition in 30 (46%) of the CKD patients. The prevalence of malnutrition in predialysis CKD patients was high in this study.
在尼日利亚,关于慢性肾脏病(CKD)患者的营养不良数据很少,尤其是在开始透析治疗之前,因此需要进行这项研究。研究对象包括从我们医院肾脏科招募的 96 名 CKD 患者。还研究了 40 名年龄和性别匹配的对照组。使用主观整体评估(SGA)、六个月随访期间的体重变化、体重指数、上臂中部周长、三头肌皮褶厚度和血清白蛋白浓度评估营养状况。使用三天的食物日记来确定患者的平均每日蛋白质摄入量。66 名 CKD 患者完成了这项研究。CKD 患者的年龄范围为 23-65 岁,平均为 47.1 ± 13.2 岁,而对照组的年龄范围为 23-65 岁,平均为 44.1 ± 14.3 岁。在研究的 66 名 CKD 患者中,有 4 名患者体重减轻了>10%。8 名(12.1%)CKD 患者的体重指数(BMI)较低(<20 kg/m),而对照组中有 3 名(7.5%)患者的 BMI<20 kg/m。7 名(10.6%)CKD 患者的血清白蛋白<3 g/dL,30 名(46%)CKD 患者的 SGA 确定存在营养不良。在这项研究中,透析前 CKD 患者的营养不良患病率很高。